Angiogenic signaling pathways and anti-angiogenic therapy for cancer

ZL Liu, HH Chen, LL Zheng, LP Sun… - Signal transduction and …, 2023 - nature.com
Angiogenesis, the formation of new blood vessels, is a complex and dynamic process
regulated by various pro-and anti-angiogenic molecules, which plays a crucial role in tumor …

Muscles, exercise and obesity: skeletal muscle as a secretory organ

BK Pedersen, MA Febbraio - Nature Reviews Endocrinology, 2012 - nature.com
During the past decade, skeletal muscle has been identified as a secretory organ.
Accordingly, we have suggested that cytokines and other peptides that are produced …

The cytokine storm in COVID-19: Further advances in our understanding the role of specific chemokines involved

F Coperchini, L Chiovato, G Ricci, L Croce… - Cytokine & Growth …, 2021 - Elsevier
SARS-COV-2 infection represents the greatest pandemic of the world, counting daily
increasing number of subjects positive to the virus and, sadly, increasing number of deaths …

Chemokine (C–X–C motif) ligand (CXCL) 10 in autoimmune diseases

A Antonelli, SM Ferrari, D Giuggioli, E Ferrannini… - Autoimmunity …, 2014 - Elsevier
Abstract (C–X–C motif) ligand (CXCL) 10 (CXCL10) belongs to the ELR− CXC subfamily
chemokine. CXCL10 exerts its function through binding to chemokine (C–X–C motif) …

Chemokines from a structural perspective

MC Miller, KH Mayo - International journal of molecular sciences, 2017 - mdpi.com
Chemokines are a family of small, highly conserved cytokines that mediate various
biological processes, including chemotaxis, hematopoiesis, and angiogenesis, and that …

Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C (high) monocytes

K Movahedi, D Laoui, C Gysemans, M Baeten… - Cancer research, 2010 - AACR
Tumor-associated macrophages (TAM) form a major component of the tumor stroma.
However, important concepts such as TAM heterogeneity and the nature of the monocytic …

Growth factors and cytokines in wound healing

S Barrientos, O Stojadinovic, MS Golinko… - Wound repair and …, 2008 - Wiley Online Library
Wound healing is an evolutionarily conserved, complex, multicellular process that, in skin,
aims at barrier restoration. This process involves the coordinated efforts of several cell types …

Regulation of wound healing by growth factors and cytokines

S Werner, R Grose - Physiological reviews, 2003 - journals.physiology.org
Werner, Sabine, and Richard Grose. Regulation of Wound Healing by Growth Factors and
Cytokines. Physiol Rev 83: 835–870, 2003; 10.1152/physrev. 00032.2002.—Cutaneous …

Immune mechanisms of pulmonary fibrosis with bleomycin

Y Ishida, Y Kuninaka, N Mukaida, T Kondo - International journal of …, 2023 - mdpi.com
Fibrosis and structural remodeling of the lung tissue can significantly impair lung function,
often with fatal consequences. The etiology of pulmonary fibrosis (PF) is diverse and …

Muscle as a secretory organ

BK Pedersen - Comprehensive physiology, 2011 - Wiley Online Library
Skeletal muscle is the largest organ in the body. Skeletal muscles are primarily
characterized by their mechanical activity required for posture, movement, and breathing …