Analysis of tissue specimens by matrix-assisted laser desorption/ionization imaging mass spectrometry in biological and clinical research

JL Norris, RM Caprioli - Chemical reviews, 2013 - ACS Publications
Human beings are adept at discerning relevant information from complex systems by
processing visual information. Similarly, as scientists labor to understand the fundamental …

Emerging computational methods in mass spectrometry imaging

H Hu, J Laskin - Advanced Science, 2022 - Wiley Online Library
Mass spectrometry imaging (MSI) is a powerful analytical technique that generates maps of
hundreds of molecules in biological samples with high sensitivity and molecular specificity …

MALDI TOF imaging mass spectrometry in clinical pathology: a valuable tool for cancer diagnostics

J Kriegsmann, M Kriegsmann… - … journal of oncology, 2014 - spandidos-publications.com
Matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) imaging mass
spectrometry (IMS) is an evolving technique in cancer diagnostics and combines the …

Robust data processing and normalization strategy for MALDI mass spectrometric imaging

JM Fonville, C Carter, O Cloarec, JK Nicholson… - Analytical …, 2012 - ACS Publications
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI)
provides localized information about the molecular content of a tissue sample. To derive …

Hyperspectral visualization of mass spectrometry imaging data

JM Fonville, CL Carter, L Pizarro, RT Steven… - Analytical …, 2013 - ACS Publications
The acquisition of localized molecular spectra with mass spectrometry imaging (MSI) has a
great, but as yet not fully realized, potential for biomedical diagnostics and research. The …

1, 5-Diaminonaphthalene hydrochloride assisted laser desorption/ionization mass spectrometry imaging of small molecules in tissues following focal cerebral …

H Liu, R Chen, J Wang, S Chen, C Xiong… - Analytical …, 2014 - ACS Publications
A sensitive analytical technique for visualizing small endogenous molecules simultaneously
is of great significance for clearly elucidating metabolic mechanisms during pathological …

[HTML][HTML] MALDI imaging mass spectrometry–painting molecular pictures

K Schwamborn, RM Caprioli - Molecular oncology, 2010 - Elsevier
MALDI Imaging Mass Spectrometry is a molecular analytical technology capable of
simultaneously measuring multiple analytes directly from intact tissue sections. Histological …

MALDI imaging mass spectrometry for direct tissue analysis: technological advancements and recent applications

B Balluff, C Schöne, H Höfler, A Walch - Histochemistry and cell biology, 2011 - Springer
Matrix assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a
method that allows the investigation of the molecular content of tissues within its …

Recent advances in mass spectrometry imaging combined with artificial intelligence for spatially clarifying molecular profiles: Toward biomedical applications

H Zhang, J Zhang, C Yuan, D Zhang, D Lu… - TrAC Trends in …, 2024 - Elsevier
Mass spectrometry imaging (MSI) is an intuitive and multidimensional analysis method that
provides spatial information on molecules in tissues or cells; it is widely used in biomedical …

Recent advances in single-cell MALDI mass spectrometry imaging and potential clinical impact

KJ Boggio, E Obasuyi, K Sugino… - Expert review of …, 2011 - Taylor & Francis
Single-cell analysis is gaining popularity in the field of mass spectrometry as a method for
analyzing protein and peptide content in cells. The spatial resolution of MALDI mass …