Recent advances in the enantioselective synthesis of chiral amines via transition metal-catalyzed asymmetric hydrogenation
A Cabré, X Verdaguer, A Riera - Chemical Reviews, 2021 - ACS Publications
Chiral amines are key structural motifs present in a wide variety of natural products, drugs,
and other biologically active compounds. During the past decade, significant advances have …
and other biologically active compounds. During the past decade, significant advances have …
Recent developments in enantioselective transition metal catalysis featuring attractive noncovalent interactions between ligand and substrate
A Fanourakis, PJ Docherty, P Chuentragool… - ACS …, 2020 - ACS Publications
Enantioselective transition metal catalysis is an area very much at the forefront of
contemporary synthetic research. The development of processes that enable the efficient …
contemporary synthetic research. The development of processes that enable the efficient …
Direct catalytic asymmetric synthesis of α-chiral primary amines
Q Yin, Y Shi, J Wang, X Zhang - Chemical Society Reviews, 2020 - pubs.rsc.org
α-Chiral primary amines are one among the most valuable and versatile building blocks for
the synthesis of numerous amine-containing pharmaceuticals and natural compounds. They …
the synthesis of numerous amine-containing pharmaceuticals and natural compounds. They …
Asymmetric hydrogenation of nonaromatic cyclic substrates
Z Zhang, NA Butt, W Zhang - Chemical reviews, 2016 - ACS Publications
Chiral cyclic structures are found in numerous natural products, pharmaceutical compounds,
and important synthetic intermediates. Asymmetric hydrogenation, allowing for the …
and important synthetic intermediates. Asymmetric hydrogenation, allowing for the …
Recent developments in the synthesis and applications of chiral ferrocene ligands and organocatalysts in asymmetric catalysis
L Cunningham, A Benson, PJ Guiry - Organic & Biomolecular …, 2020 - pubs.rsc.org
With the ever-present need for novel asymmetric methodologies in organic synthesis to
allow chemists to access enantiopure compounds, so too is there a need for new chiral …
allow chemists to access enantiopure compounds, so too is there a need for new chiral …
The industrial age of biocatalytic transamination
M Fuchs, JE Farnberger… - European Journal of …, 2015 - Wiley Online Library
During the last decade the use of ω‐transaminases has been identified as a very powerful
method for the preparation of optically pure amines from the corresponding ketones. Their …
method for the preparation of optically pure amines from the corresponding ketones. Their …
Optical analysis of reaction yield and enantiomeric excess: a new paradigm ready for prime time
BT Herrera, SL Pilicer, EV Anslyn… - Journal of the …, 2018 - ACS Publications
This Perspective highlights the advances of optical methods for asymmetric reaction
discovery. Optical analysis allows for the determination of absolute configuration …
discovery. Optical analysis allows for the determination of absolute configuration …
Circular dichroism sensing: Strategies and applications
JSSK Formen, JR Howard, EV Anslyn… - Angewandte Chemie …, 2024 - Wiley Online Library
The analysis of the absolute configuration, enantiomeric composition, and concentration of
chiral compounds are frequently encountered tasks across the chemical and health …
chiral compounds are frequently encountered tasks across the chemical and health …
Strong Brønsted acid promoted asymmetric hydrogenation of isoquinolines and quinolines catalyzed by a Rh–thiourea chiral phosphine complex via anion binding
Rhodium catalyzed asymmetric hydrogenation of both isoquinolines and quinolines
provides a new method to synthesize chiral tetrahydroisoquinolines and …
provides a new method to synthesize chiral tetrahydroisoquinolines and …