Photochemical and electrochemical applications of proton-coupled electron transfer in organic synthesis

PRD Murray, JH Cox, ND Chiappini, CB Roos… - Chemical …, 2021 - ACS Publications
We present here a review of the photochemical and electrochemical applications of multi-
site proton-coupled electron transfer (MS-PCET) in organic synthesis. MS-PCETs are redox …

An overview of coumarin as a versatile and readily accessible scaffold with broad-ranging biological activities

F Annunziata, C Pinna, S Dallavalle… - International Journal of …, 2020 - mdpi.com
Privileged structures have been widely used as an effective template for the research and
discovery of high value chemicals. Coumarin is a simple scaffold widespread in Nature and …

Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates

AJ Vegas, O Veiseh, JC Doloff, M Ma, HH Tam… - Nature …, 2016 - nature.com
The foreign body response is an immune-mediated reaction that can lead to the failure of
implanted medical devices and discomfort for the recipient,,,,,. There is a critical need for …

Click chemistry for drug development and diverse chemical–biology applications

P Thirumurugan, D Matosiuk, K Jozwiak - Chemical reviews, 2013 - ACS Publications
Chemistry, traditionally being the science of synthesis and structural manipulations of
molecules, has gradually undertaken the more challenging task of biology-oriented …

Benefits and applications of microwave-assisted synthesis of nitrogen containing heterocycles in medicinal chemistry

M Henary, C Kananda, L Rotolo, B Savino, EA Owens… - RSC …, 2020 - pubs.rsc.org
Nitrogen containing heterocycles are of immense research interest because they are often
found as naturally occurring bioactive compounds. The prominence of N-heterocycles …

Coumarin–benzimidazole hybrids: A review of developments in medicinal chemistry

R Gondru, Y Li, J Banothu - European Journal of Medicinal Chemistry, 2022 - Elsevier
Coumarin and benzimidazole are privileged structures in medicinal chemistry and are
widely used in drug discovery and development due to their vast biological properties. The …

Click chemistry: 1, 2, 3‐triazoles as pharmacophores

SG Agalave, SR Maujan… - Chemistry–An Asian …, 2011 - Wiley Online Library
Abstract The copper (I)‐catalyzed 1, 2, 3‐triazole‐forming reaction between azides and
terminal alkynes has become the gold standard of 'click chemistry'due to its reliability …

Design, synthesis, biological evaluation and molecular docking studies of novel 1H-1, 2, 3-Triazole derivatives as potent inhibitors of carbonic anhydrase …

DA Anil, BO Aydin, Y Demir, B Turkmenoglu - Journal of Molecular …, 2022 - Elsevier
Triazole compounds have garnered significant interest due to their wide range of
pharmacological activities and ease of synthesis. Click chemistry is a synthetic method …

Azole-based energetic salts

H Gao, JM Shreeve - Chemical reviews, 2011 - ACS Publications
Energetic materials include explosives, propellants, and pyrotechnics that are used for a
variety of military purposes and civilian applications. 1Ā3 An explosive is defined as a …

A review on the biomedical efficacy of transition metal triazole compounds

SH Sumrra, W Zafar, M Imran… - Journal of Coordination …, 2022 - Taylor & Francis
From the apocalyptic era of antibiotic resistance, the scientific community around the world is
engaged in designing and developing metal-based compounds to inhibit and control …