Charged and polar groups, through forming ion pairs, hydrogen bonds, and other less
specific electrostatic interactions, impart important properties to proteins. Modulation of the …

The signaling molecule auxin coordinates many growth and development processes in
plants, mainly through modulating gene expression. Transcriptional response is mediated …

The relationship between DNA sequence recognition and catalytic specificity in a DNA-
modifying enzyme was explored using paramagnetic Cu2+ ions as probes for ESR …

We used adaptive umbrella sampling on a modified version of the roll angle to simulate the
bending of DNA dodecamers. Simulations were carried out with the AMBER and CHARMM …

The dynamics and mechanism of how site-specific DNA-bending proteins initially interrogate
potential binding sites prior to recognition have remained elusive for most systems. Here we …

Phosphazene chemistry continues to expand in its breadth and application. This article
discusses new research published in 2013 covering mono-and dimeric structures …

The binding of EcoR1 to a 90-bp DNA duplex attached to colloidal microparticles and the
subsequent cleavage by the enzyme was observed in real time and label-free with time …

The DNA binding stringency of restriction endonucleases is crucial for their proper function.
The X‐ray structures of the specific and non‐cognate complexes of the restriction nuclease …

Poisson's ratio σ in linear elasticity theory is the ratio of the transverse compression of a rod
to its longitudinal extension. For common macroscopic materials, σ is a positive quantity …

As a novel approach to the structural and functional properties that give rise to extremely
stringent sequence specificity in protein–DNA interactions, we have exploited “promiscuous” …