A comprehensive review on phytochemistry, pharmacology, and flavonoid biosynthesis of Scutellaria baicalensis

ZL Wang, S Wang, Y Kuang, ZM Hu, X Qiao… - Pharmaceutical …, 2018 - Taylor & Francis
Abstract Context: Scutellaria baicalensis Georgi (Lamiaceae) is a popular medicinal plant.
Its roots are used as the famous traditional Chinese medicine Huang-Qin, which is recorded …

Natural products against Alzheimer's disease: Pharmaco-therapeutics and biotechnological interventions

A Dey, R Bhattacharya, A Mukherjee… - Biotechnology advances, 2017 - Elsevier
Alzheimer's disease (AD) is a severe, chronic and progressive neurodegenerative disease
associated with memory and cognition impairment ultimately leading to death. It is the …

Baicalin mediated regulation of key signaling pathways in cancer

S Singh, A Meena, S Luqman - Pharmacological research, 2021 - Elsevier
Baicalin has been widely investigated against different types of malignancies both at the
cellular and molecular levels over the past few years. Due to its remarkable anti-proliferative …

Pharmacokinetics and bioavailability enhancement of baicalin: a review

T Huang, Y Liu, C Zhang - European Journal of Drug Metabolism and …, 2019 - Springer
Baicalin is one of the major bioactive components of Scutellaria radix, a Chinese herb that
has been used since ancient times. Baicalin has various pharmacological activities …

Identification of baicalein as a ferroptosis inhibitor by natural product library screening

Y Xie, X Song, X Sun, J Huang, M Zhong… - Biochemical and …, 2016 - Elsevier
Ferroptosis, a novel form of regulated cell death, is characterized by oxidative injury from
iron accumulation and lipid peroxidation. In a natural product library screening for ferroptosis …

The potential of flavonoids and flavonoid metabolites in the treatment of neurodegenerative pathology in disorders of cognitive decline

J Melrose - Antioxidants, 2023 - mdpi.com
Flavonoids are a biodiverse family of dietary compounds that have antioxidant, anti-
inflammatory, antiviral, and antibacterial cell protective profiles. They have received …

Inhibiting toxic aggregation of amyloidogenic proteins: a therapeutic strategy for protein misfolding diseases

B Cheng, H Gong, H Xiao, RB Petersen… - … et Biophysica Acta (BBA …, 2013 - Elsevier
Background The deposition of self-assembled amyloidogenic proteins is associated with
multiple diseases, including Alzheimer's disease, Parkinson's disease and type 2 diabetes …

Baicalein Inhibits Staphylococcus aureus Biofilm Formation and the Quorum Sensing System In Vitro

Y Chen, T Liu, KE Wang, C Hou, S Cai, Y Huang… - PLoS …, 2016 - journals.plos.org
Biofilm formed by Staphylococcus aureus significantly enhances antibiotic resistance by
inhibiting the penetration of antibiotics, resulting in an increasingly serious situation. This …

Neuroprotective and cognitive enhancement potentials of baicalin: a review

K Sowndhararajan, P Deepa, M Kim, SJ Park, S Kim - Brain Sciences, 2018 - mdpi.com
Neurodegenerative diseases are a heterogeneous group of disorders that are characterized
by the gradual loss of neurons. The development of effective neuroprotective agents to …

Oroxylum indicum (L.) Kurz, an important Asian traditional medicine: from traditional uses to scientific data for its commercial exploitation

B Dinda, I SilSarma, M Dinda, P Rudrapaul - Journal of …, 2015 - Elsevier
Ethnopharmacological relevance Oroxylum indicum\(L.) Kurz has been used for centuries as
a traditional medicine in Asia in ethnomedicinal systems for the prevention and treatment of …