Population genomics of Klebsiella pneumoniae

KL Wyres, MMC Lam, KE Holt - Nature Reviews Microbiology, 2020 - nature.com
Klebsiella pneumoniae is a common cause of antimicrobial-resistant opportunistic infections
in hospitalized patients. The species is naturally resistant to penicillins, and members of the …

Carbapenem-Resistant Klebsiella pneumoniae: Virulence Factors, Molecular Epidemiology and Latest Updates in Treatment Options

T Karampatakis, K Tsergouli, P Behzadi - Antibiotics, 2023 - mdpi.com
Klebsiella pneumoniae is a Gram-negative opportunistic pathogen responsible for a variety
of community and hospital infections. Infections caused by carbapenem-resistant K …

A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex

MMC Lam, RR Wick, SC Watts, LT Cerdeira… - Nature …, 2021 - nature.com
Klebsiella pneumoniae is a leading cause of antimicrobial-resistant (AMR) healthcare-
associated infections, neonatal sepsis and community-acquired liver abscess, and is …

Klebsiella species: Taxonomy, hypervirulence and multidrug resistance

N Dong, X Yang, EWC Chan, R Zhang, S Chen - EBioMedicine, 2022 - thelancet.com
Members of the genus Klebsiella have rapidly evolved within the past decade, generating
organisms that simultaneously exhibit both multidrug resistance and hypervirulence (MDR …

Hypervirulent Klebsiella pneumoniae – clinical and molecular perspectives

JE Choby, J Howard‐Anderson… - Journal of internal …, 2020 - Wiley Online Library
Hypervirulent Klebsiella pneumoniae (hvKp) has emerged as a concerning global
pathogen. hvKp is more virulent than classical K. pneumoniae (cKp) and capable of causing …

The Changing Face of the Family Enterobacteriaceae (Order: “Enterobacterales”): New Members, Taxonomic Issues, Geographic Expansion, and New Diseases and …

JM Janda, SL Abbott - Clinical microbiology reviews, 2021 - Am Soc Microbiol
The family Enterobacteriaceae has undergone significant morphogenetic changes in its
more than 85-year history, particularly during the past 2 decades (2000 to 2020). The …

[HTML][HTML] A global perspective on the convergence of hypervirulence and carbapenem resistance in Klebsiella pneumoniae

P Lan, Y Jiang, J Zhou, Y Yu - Journal of global antimicrobial resistance, 2021 - Elsevier
Hypervirulence and carbapenem resistance have emerged as two distinct evolutionary
directions for Klebsiella pneumoniae, which pose a great threat in clinical settings. Multiple …

Virulence Factors in Hypervirulent Klebsiella pneumoniae

J Zhu, T Wang, L Chen, H Du - Frontiers in microbiology, 2021 - frontiersin.org
Hypervirulent Klebsiella pneumoniae (hvKP) has spread globally since first described in the
Asian Pacific Rim. It is an invasive variant that differs from the classical K. pneumoniae …

Carbapenem resistance-encoding and virulence-encoding conjugative plasmids in Klebsiella pneumoniae

X Yang, N Dong, EWC Chan, R Zhang, S Chen - Trends in microbiology, 2021 - cell.com
Klebsiella pneumoniae has an exceptional ability to acquire exogenous resistance-
encoding and hypervirulence-encoding genetic elements. In this review we trace the key …

Molecular epidemiology of carbapenem-resistant hypervirulent Klebsiella pneumoniae in China

X Yang, Q Sun, J Li, Y Jiang, Y Li, J Lin… - Emerging microbes & …, 2022 - Taylor & Francis
The epidemiological features of the newly emerged carbapenem-resistant hypervirulent
Klebsiella pneumoniae (CR-HvKP) and its potential threat to human health are currently …