Triazole hybrid compounds: A new frontier in malaria treatment
Reviewing the advancements in malaria treatment, the emergence of triazole hybrid
compounds stands out as a groundbreaking development. Combining the advantages of …
compounds stands out as a groundbreaking development. Combining the advantages of …
[HTML][HTML] Metal complexes with Schiff bases: Data collection and recent studies on biological activities
MS Sinicropi, J Ceramella, D Iacopetta… - International Journal of …, 2022 - mdpi.com
Metal complexes play a crucial role in pharmaceutical sciences owing to their wide and
significant activities. Schiff bases (SBs) are multifaceted pharmacophores capable of forming …
significant activities. Schiff bases (SBs) are multifaceted pharmacophores capable of forming …
Profiling the structural determinants of pyrrolidine derivative as gelatinases (MMP-2 and MMP-9) inhibitors using in silico approaches
Quantitative structure activity relationship (QSAR) studies on pyrrolidine derivatives have
been established using CoMFA, CoMSIA, and Hologram QSAR analysis to estimate the …
been established using CoMFA, CoMSIA, and Hologram QSAR analysis to estimate the …
Synthesis, characterization, molecular dynamic simulation, and biological assessment of cinnamates linked to imidazole/benzimidazole as a CYP51 inhibitor
Abstract A class of 2-(1 H-imidazol-1-yl)-1-phenylethyl cinnamates 6a-6j and 2-(1 H-benzo
[d] imidazol-1-yl)-1-phenylethyl cinnamates 7a-7j were synthesized, and their synthesis was …
[d] imidazol-1-yl)-1-phenylethyl cinnamates 7a-7j were synthesized, and their synthesis was …
The versatile nature of indole containing Schiff bases: A mini review
T Sanjurani, P Barman - Polyhedron, 2023 - Elsevier
Carbonyl compounds such as aldehydes or ketones condense with amines to form Schiff
bases. The synthesis of Schiff bases containing indole rings yields a broad spectrum of …
bases. The synthesis of Schiff bases containing indole rings yields a broad spectrum of …
Synthesis, docking, and biological investigations of new coumarin-piperazine hybrids as potential antibacterial and anticancer agents
Structurally diversified coumarin analogs were found to display a remarkable array of affinity
with the different molecular targets. 4-hydroxy-7-methylcoumarin was synthesized from m …
with the different molecular targets. 4-hydroxy-7-methylcoumarin was synthesized from m …
Antibacterial potential of trihydroxycyclohexa-2, 4-diene-1-carboxylic acid: Insight from DFT, molecular docking, and molecular dynamic simulation
Abstract In this study,(z)-5-((3-(2, 3-dihydroxyphenyl) acryloyl) oxy)-1, 3, 4-
trihydroxycyclohexa-2, 4-diene-1-carboxylic acid (chlorogenic acid) was isolated and …
trihydroxycyclohexa-2, 4-diene-1-carboxylic acid (chlorogenic acid) was isolated and …
[HTML][HTML] Thymus musilii Velen. Methanolic Extract: In Vitro and In Silico Screening of Its Antimicrobial, Antioxidant, Anti-Quorum Sensing, Antibiofilm, and Anticancer …
Thymus musilii Velen. is a rare plant species cultivated in the Ha'il region (Saudi Arabia)
under greenhouse conditions. In this work, we described, for the first time, the phytochemical …
under greenhouse conditions. In this work, we described, for the first time, the phytochemical …
Exploring the antimalarial, antioxidant and antimicrobial properties of newly synthesized diorganotin (IV) complexes with ONO-donor hydrazone ligands
Inspired by the role of organotin (IV) compounds as potential pharmaceutical agents, we
have synthesized a series of new diorganotin (IV) complexes (5–20) of hydrazone ligands (1 …
have synthesized a series of new diorganotin (IV) complexes (5–20) of hydrazone ligands (1 …
Development of isopropyl-tailed chalcones as a new class of selective MAO-B inhibitors for the treatment of Parkinson's disorder
S Kumar, JM Oh, MA Abdelgawad, MAS Abourehab… - ACS …, 2023 - ACS Publications
Thirteen isopropyl chalcones (CA1–CA13) were synthesized and evaluated for their
inhibitory activity against monoamine oxidase (MAO). All compounds inhibited MAO-B more …
inhibitory activity against monoamine oxidase (MAO). All compounds inhibited MAO-B more …