This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

Over the past decade, numerous studies have shown that increased aortic stiffness is
associated with major cardiovascular disease end points, including heart disease, stroke …

The vascular myogenic response refers to the acute reaction of a blood vessel to a change
in transmural pressure. This response is critically important for the development of resting …

The regulation of blood flow has rich history of investigation and is exemplified in exercising
skeletal muscle by a concerted interaction between striated muscle fibers and their …

Blood flow (BF) increases with increasing exercise intensity in skeletal, respiratory, and
cardiac muscle. In humans during maximal exercise intensities, 85% to 90% of total cardiac …

Glaucoma is an optic neuropathy of unknown origin. The most important risk factor for the
disease is an increased intraocular pressure (IOP). Reducing IOP is associated with …

Hypertension is known to be associated with an increase in the wall/lumen ratio (W/L) of the
resistance arteries. Growth, eutrophic remodelling and changes in arterial distensibility can …

In the last decade, the pathophysiology of microcirculation has become an actively
developing field of hypertension research, which we have felt it useful to review. An exact …

Skeletal muscle blood flow capacity (BFC) is increased by exercise training due to structural
vascular remodeling (in the form of angiogenesis of capillaries and remodeling of the arterial …

The smooth muscle of arterioles responds to an increase in intraluminal pressure with
vasoconstriction and with vasodilation when pressure is decreased. Such myogenic …