The modeling of time to event data is an important topic with many applications in diverse
areas. The collective of methods to analyze such data are called survival analysis, event …

The NF-kB1 gene belongs to the family of transcription factors that are involved in the
regulation of a wide range of biological reactions. It has been established that NF-kB1 plays …

Mutations in breast cancer type 1 susceptibility protein (BRCA1) and its heterodimeric
binding partner BARD1 confer a high risk for the development of breast and ovarian …

The role of the transcription factor NF-κB in shaping the cancer microenvironment is
becoming increasingly clear. Inflammation alters the activity of enzymes that modulate NF …

The role of PD‐L1 as a prognostic and predictive biomarker is an area of great interest.
However, there is a lack of consensus on how to deliver PD‐L1 as a clinical biomarker. At …

The SRC-family kinase LYN is highly expressed in triple-negative/basal-like breast cancer
(TNBC) and in the cell of origin of these tumors, c-KIT-positive luminal progenitors. Here, we …

The digitalization of all areas of science, industry, and society has led to an unprecedented
flood of data. However, after the initial enthusiasm for the anticipated wealth of information …

Beyond prophylactic mastectomy, there are currently very few options available to BRCA1
mutation carriers to help reduce their risk of developing breast cancer. An effective …

Cathepsin S (CTSS) has previously been implicated in a number of cancer types, where it is
associated with poor clinical features and outcome. To date, patient outcome in breast …

Breast cancer is characterized as being a heterogeneous pathology with a broad phenotype
variability. Breast cancer subtypes have been developed in order to capture some of this …