Thermal ablation of tumours: biological mechanisms and advances in therapy
Minimally invasive thermal ablation of tumours has become common since the advent of
modern imaging. From the ablation of small, unresectable tumours to experimental …
modern imaging. From the ablation of small, unresectable tumours to experimental …
Cancer vaccines
LH Butterfield - Bmj, 2015 - bmj.com
Cancer vaccines are designed to promote tumor specific immune responses, particularly
cytotoxic CD8 positive T cells that are specific to tumor antigens. The earliest vaccines …
cytotoxic CD8 positive T cells that are specific to tumor antigens. The earliest vaccines …
More than just tumor destruction: immunomodulation by thermal ablation of cancer
Over the past decades, thermoablative techniques for the therapy of localized tumors have
gained importance in the treatment of patients not eligible for surgical resection. Anecdotal …
gained importance in the treatment of patients not eligible for surgical resection. Anecdotal …
Phase I dose-escalation study of stereotactic body radiotherapy in patients with hepatic metastases
W Rule, R Timmerman, L Tong, R Abdulrahman… - Annals of surgical …, 2011 - Springer
Purpose To identify a tolerable and effective dose for 5-fraction stereotactic body
radiotherapy for hepatic metastases. Methods Patients were enrolled onto three dose …
radiotherapy for hepatic metastases. Methods Patients were enrolled onto three dose …
Radiofrequency thermal ablation for hepatocellular carcinoma stimulates autologous NK-cell response
A Zerbini, M Pilli, D Laccabue, G Pelosi, A Molinari… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Radiofrequency thermal ablation (RFA) is a minimally invasive
technique used as standard local therapy of hepatocellular carcinoma and second-line …
technique used as standard local therapy of hepatocellular carcinoma and second-line …
Irreversible electroporation induces CD8+ T cell immune response against post-ablation hepatocellular carcinoma growth
Z Dai, Z Wang, K Lei, J Liao, Z Peng, M Lin, P Liang… - Cancer Letters, 2021 - Elsevier
Ablative treatment evokes antitumor immunity, but knowledge on the emerging irreversible
electroporation (IRE)-induced immunity in hepatocellular carcinoma (HCC) is limited. To …
electroporation (IRE)-induced immunity in hepatocellular carcinoma (HCC) is limited. To …
Irreversible electroporation versus radiofrequency ablation: a comparison of local and systemic effects in a small-animal model
BE Bulvik, N Rozenblum, S Gourevich, M Ahmed… - Radiology, 2016 - pubs.rsna.org
Purpose To compare both periablational and systemic effects of two mechanistically different
types of ablation: thermal radiofrequency (RF) ablation and electroporative ablation with …
types of ablation: thermal radiofrequency (RF) ablation and electroporative ablation with …
The synergistic effect of interventional locoregional treatments and immunotherapy for the treatment of hepatocellular carcinoma
N Brandi, M Renzulli - International Journal of Molecular Sciences, 2023 - mdpi.com
Immunotherapy has remarkably revolutionized the management of advanced HCC and
prompted clinical trials, with therapeutic agents being used to selectively target immune cells …
prompted clinical trials, with therapeutic agents being used to selectively target immune cells …
Focused ultrasound: tumour ablation and its potential to enhance immunological therapy to cancer
Various kinds of image-guided techniques have been successfully applied in the last years
for the treatment of tumours, as alternative to surgical resection. High intensity focused …
for the treatment of tumours, as alternative to surgical resection. High intensity focused …
Injectable immunotherapeutic thermogel for enhanced immunotherapy post tumor radiofrequency ablation
Tumor radiofrequency ablation (RFA) is a local and minimally invasive application using
high temperature to induce coagulative necrosis of tumor, which has been commonly used …
high temperature to induce coagulative necrosis of tumor, which has been commonly used …