Anticancer and antimicrobial activities of naproxen and naproxen derivatives
Mİ Han, ŞG Küçükgüzel - Mini reviews in medicinal chemistry, 2020 - ingentaconnect.com
This review explains the effects of naproxen and the naproxen moiety in important biological
activities. Naproxen, 2-(6-methoxynaphthalen-2-yl) propionic acid, is one of the most utilized …
activities. Naproxen, 2-(6-methoxynaphthalen-2-yl) propionic acid, is one of the most utilized …
Arylpropionic acid-derived NSAIDs: New insights on derivatization, anticancer activity and potential mechanism of action
NSAIDs displayed chemopreventive and anticancer effects against several types of cancers.
Moreover, combination of NSAIDs with anticancer agents resulted in enhanced anticancer …
Moreover, combination of NSAIDs with anticancer agents resulted in enhanced anticancer …
Design and synthesis of novel (S)-Naproxen hydrazide-hydrazones as potent VEGFR-2 inhibitors and their evaluation in vitro/in vivo breast cancer models
Naproxen is a common non-steroidal anti-inflammatory drug, which is the most usually used
propionic acid derivative for the treatment of many types of diseases. In this study, a series of …
propionic acid derivative for the treatment of many types of diseases. In this study, a series of …
Synthesis and anticancer activity of novel hydrazone linkage-based aryl sulfonate derivatives as apoptosis inducers
In the present study, the various 28 hybrid molecules containing hydrazone and sulfonate
moieties were synthesized and characterized by FTIR, 1H-NMR, 13C-NMR spectroscopy …
moieties were synthesized and characterized by FTIR, 1H-NMR, 13C-NMR spectroscopy …
Synthesis, molecular modeling, in vivo study, and anticancer activity of 1,2,4‐triazole containing hydrazide–hydrazones derived from (S)‐naproxen
Abstract A new series of 1, 2, 4‐triazole containing hydrazide–hydrazones derived from (S)‐
naproxen (7a–m) was synthesized in this study. The structures of these compounds were …
naproxen (7a–m) was synthesized in this study. The structures of these compounds were …
Design, synthesis, and anticancer evaluation of novel tetracaine hydrazide-hydrazones
Mİ Han, N Imamoglu - ACS omega, 2023 - ACS Publications
Tetracaine is an ester derivative used as a local anesthetic molecule. In this study, a series
of novel Tetracaine derivatives bearing hydrazide-hydrazone moiety were designed …
of novel Tetracaine derivatives bearing hydrazide-hydrazone moiety were designed …
Design, synthesis and anticancer activity studies of novel 4-butylaminophenyl hydrazide-hydrazones as apoptotic inducers
In this study, a series of the novel Tetracaine derivatives bearing hydrazide-hydrazone
moiety were designed, synthesized, and evaluated for anticancer activity. The structures of …
moiety were designed, synthesized, and evaluated for anticancer activity. The structures of …
Synthesis, molecular modeling, in vivo study and anticancer activity against prostate cancer of (+)(S)-naproxen derivatives
Abstract In this study,(S)-naproxen thiosemicarbazides (3a-d), 1, 2, 4-triazoles (4a-c),
triazole-thioether hybride compounds (5a-p) were synthesized and their structures (3a, 3d …
triazole-thioether hybride compounds (5a-p) were synthesized and their structures (3a, 3d …
Thioethers: an overview
MI Han, Ŧ Küçükgüzel - Current drug targets, 2022 - ingentaconnect.com
Spreading rapidly in recent years, cancer has become one of the causes of the highest
mortality rates after cardiovascular diseases. The reason for cancer development is still not …
mortality rates after cardiovascular diseases. The reason for cancer development is still not …
Recent developments in the chemistry of 1H-and 4H-1, 2, 4-triazoles
Abstract 1H-and 4H-1, 2, 4-Triazoles have wide potent biological applications; therefore,
developing new synthetic routes for such interesting scaffolds is of great importance. The …
developing new synthetic routes for such interesting scaffolds is of great importance. The …