Understanding human aging and the fundamental cell signaling link in age-related diseases: the middle-aging hypovascularity hypoxia hypothesis

TJ Phua - Frontiers in aging, 2023 - frontiersin.org
Aging-related hypoxia, oxidative stress, and inflammation pathophysiology are closely
associated with human age-related carcinogenesis and chronic diseases. However, the …

[HTML][HTML] Enhanced sciatic nerve regeneration by relieving iron-overloading and organelle stress with the nanofibrous P (MMD-co-LA)/DFO conduits

L Han, X Dong, T Qiu, Z Dou, L Wu, H Dai - Materials Today Bio, 2022 - Elsevier
Wallerian degeneration after peripheral nerve injury (PNI), that is, the autonomous
degeneration of distal axons, leads to an imbalance of iron homeostasis and easily induces …

Carbon monoxide therapy using hybrid carbon monoxide-releasing/Nrf2-inducing molecules through a neuroprotective lens

F Cavicchioli, IM Cesarotti, M Fangman, J Lua… - Chemistry, 2021 - mdpi.com
Carbon monoxide (CO) has long been known for its toxicity. However, in recent decades,
new applications for CO as a therapeutic compound have been proposed, and multiple …

营养成分改善环境污染物暴露所致不良健康效应的可能作用机制

夏转宁, 田英, 高宇 - 环境与职业医学, 2022 - jeom.org
环境污染物暴露是影响人类健康的重要危险因素. 近年来, 有研究证据表明一些营养成分能够
改善环境污染物暴露造成的不良健康效应. 因此, 考虑如何利用这些营养成分进行有效的营养 …

Two fighters against oxidative stress in peripheral organs in Parkinson's Disease: Brain-derived neurotrophic factor and hydrogen sulfide

BT Yavuz, C Şirin, C Tomruk, G Hacıoğlu… - Ege Tıp …, 2024 - egetipdergisi.com.tr
Aim: Parkinson's disease, which is a neurodegenerative disorder, has adverse
consequences on peripheral organs as well as the brain. This study aims to investigate the …