[HTML][HTML] Metabolic reprogramming in triple-negative breast cancer

Z Wang, Q Jiang, C Dong - Cancer biology & medicine, 2020 - ncbi.nlm.nih.gov
Since triple-negative breast cancer (TNBC) was first defined over a decade ago, increasing
studies have focused on its genetic and molecular characteristics. Patients diagnosed with …

Triple negative breast cancer in the era of miRNA

H Sabit, E Cevik, H Tombuloglu, S Abdel-Ghany… - Critical reviews in …, 2021 - Elsevier
The objective of this review is to elucidate the role of miRNAs in triple negative breast cancer
(TNBC). To achieve our goal, we searched databases such as PubMed, ScienceDirect …

Involvement of the kynurenine pathway in breast cancer: updates on clinical research and trials

HN Girithar, A Staats Pires, SB Ahn… - British Journal of …, 2023 - nature.com
Breast cancer (BrCa) is the leading cause of cancer incidence and mortality in women
worldwide. While BrCa treatment has been shown to be highly successful if detected at an …

Potential of the miR-200 family as a target for developing anti-cancer therapeutics

H Jo, K Shim, D Jeoung - International Journal of Molecular Sciences, 2022 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs (18–24 nucleotides) that play significant
roles in cell proliferation, development, invasion, cancer development, cancer progression …

A systematic review on the therapeutic potentiality of PD-L1-inhibiting microRNAs for triple-negative breast cancer: Toward single-cell sequencing-guided biomimetic …

MA Shadbad, S Safaei, O Brunetti, A Derakhshani… - Genes, 2021 - mdpi.com
The programmed death-ligand 1 (PD-L1)/programmed cell death protein 1 (PD-1) is a well-
established inhibitory immune checkpoint axis in triple-negative breast cancer (TNBC) …

Mesenchymal stem cell-derived exosomes as new tools for delivery of miRNAs in the treatment of cancer

A Dalmizrak, O Dalmizrak - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Although ongoing medical research is working to find a cure for a variety of cancers, it
continues to be one of the major causes of death worldwide. Chemotherapy and …

Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors

RK Powers, R Culp-Hill, MP Ludwig, KP Smith… - Nature …, 2019 - nature.com
Abstract Trisomy 21 (T21) causes Down syndrome (DS), affecting immune and neurological
function by ill-defined mechanisms. Here we report a large metabolomics study of plasma …

Phenotypic heterogeneity of triple-negative breast cancer mediated by epithelial–mesenchymal plasticity

B Kvokačková, J Remšík, MK Jolly, K Souček - Cancers, 2021 - mdpi.com
Simple Summary Epithelial–mesenchymal transition (EMT) and its reverse process
mesenchymal–epithelial transition (MET) are considered critical events in the cancer …

Cell-free miRNAs as non-invasive biomarkers in breast cancer: Significance in early diagnosis and metastasis prediction

D Kashyap, H Kaur - Life sciences, 2020 - Elsevier
Breast cancer is one of the genetic diseases causing a high mortality among women around
the world. Despite the availability of advanced diagnostic tools and treatment strategies, the …

Therapeutic potential of tumor metabolic reprogramming in triple-negative breast cancer

G Munkácsy, L Santarpia, B Győrffy - International Journal of Molecular …, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, with
clinical features of high metastatic potential, susceptibility to relapse, and poor prognosis …