The role of tumor necrosis factor in manipulating the immunological response of tumor microenvironment

D Laha, R Grant, P Mishra, N Nilubol - Frontiers in immunology, 2021 - frontiersin.org
The tumor microenvironment (TME) is an intricate system within solid neoplasms. In this
review, we aim to provide an updated insight into the TME with a focus on the effects of …

MicroRNAs: Potential candidates for diagnosis and treatment of colorectal cancer

A Moridikia, H Mirzaei, A Sahebkar… - Journal of cellular …, 2018 - Wiley Online Library
Colorectal cancer (CRC) is known as the third common cancer worldwide and an important
public health problem in different populations. Several genetics and environmental risk …

The interplay among miRNAs, major cytokines, and cancer-related inflammation

C Chakraborty, AR Sharma, G Sharma… - Molecular Therapy-Nucleic …, 2020 - cell.com
Inflammation is closely related with the progression of cancer and is an indispensable
component that orchestrates the tumor microenvironment. Studies suggest that different …

miR-19a promotes colorectal cancer proliferation and migration by targeting TIA1

Y Liu, R Liu, F Yang, R Cheng, X Chen, S Cui, Y Gu… - Molecular cancer, 2017 - Springer
Background Colorectal cancer (CRC) is a major worldwide health problem due to its high
prevalence and mortality rate. T-cell intracellular antigen 1 (TIA1) is an important tumor …

Regulation of TH17 Cells and Associated Cytokines in Wound Healing, Tissue Regeneration, and Carcinogenesis

L Brockmann, AD Giannou, N Gagliani… - International journal of …, 2017 - mdpi.com
Wound healing is a crucial process which protects our body against permanent damage and
invasive infectious agents. Upon tissue damage, inflammation is an early event which is …

Exosomal miRNAs as biomarkers of recurrent lung cancer

R Munagala, F Aqil, RC Gupta - Tumor Biology, 2016 - Springer
Prognosis of lung cancer still remains grim largely due to recurrence and aggressive
metastasis of the disease. In this study, we examined the potential of exosomal miRNAs as …

[HTML][HTML] Chemokines and chemokine receptors in colorectal cancer; multifarious roles and clinical impact

M Braoudaki, MS Ahmad, D Mustafov, S Seriah… - Seminars in Cancer …, 2022 - Elsevier
Colorectal cancer (CRC) is considered the second cause of cancer death worldwide. The
early diagnosis plays a key role in patient prognosis and subsequently overall survival …

Emerging roles of ferroptosis-related miRNAs in tumor metastasis

Z Jiang, J Zhou, J Deng, L Li, R Wang, Y Han… - Cell death …, 2023 - nature.com
Ferroptosis, a novel mode of cell death dependent on iron and reactive oxygen species, has
been extensively explored during malignant tumors metastasis. Ferroptosis can interact with …

MicroRNAs, long noncoding RNAs, and circular RNAs: potential tumor biomarkers and targets for colorectal cancer

S Yang, Z Sun, Q Zhou, W Wang, G Wang… - Cancer management …, 2018 - Taylor & Francis
Noncoding RNAs (ncRNAs) can be divided into microRNAs (miRNAs), long noncoding
RNAs (lncRNAs), circular RNAs (circRNAs), pRNAs, and tRNAs. Traditionally, miRNAs exert …

Biological implications and clinical potential of metastasis-related miRNA in colorectal cancer

L Niu, W Yang, L Duan, X Wang, Y Li, C Xu… - … Therapy-Nucleic Acids, 2021 - cell.com
Colorectal cancer (CRC), ranking as the third commonest cancer, leads to extremely high
rates of mortality. Metastasis is the major cause of poor outcome in CRC. When metastasis …