Although, better known for its role in inflammation, the transcription factor nuclear factor
kappa B (NF-κB) has more recently been implicated in synaptic plasticity, learning, and …

What evolutionary events led to the emergence of human cognition? Although the genetic
differences separating modern humans from both non-human primates (for example …

The Hippo pathway is crucial in organ size control, and its dysregulation contributes to
tumorigenesis. However, upstream signals that regulate the mammalian Hippo pathway …

Autism spectrum disorder (ASD) is a genetically heterogeneous condition, caused by a
combination of rare de novo and inherited variants as well as common variants in at least …

Although many transcription factors are known to control important aspects of neural
development, the genome-wide programs that are directly regulated by these factors are not …

Over the course of ontogenesis, the human brain and human cognitive abilities develop in
parallel, resulting in a phenotype strikingly distinct from that of other primates. Here, we used …

The capacity to remember our past experiences and organize our future draws on a number
of cognitive processes that allow our brain to form and store neural representations that can …

The brain is a highly adaptable organ that is capable of converting sensory information into
changes in neuronal function. This plasticity allows behavior to be accommodated to the …

Background Schizophrenia is a complex brain disorder with molecular mechanisms that
have yet to be elucidated. Previous studies have suggested that changes in gene …

Background Alzheimer's disease (AD) is characterized by a neurodegenerative progression
that alters cognition. On a phenotypical level, cognition is evaluated by means of the …