[HTML][HTML] [15O] H2O PET: potential or essential for Molecular Imaging?

RHJA Slart, TS Martinez-Lucio, HH Boersma… - Seminars in Nuclear …, 2024 - Elsevier
Imaging water pathways in the human body provides an excellent way of measuring
accurately the blood flow directed to different organs. This makes it a powerful diagnostic …

Prospective of 68Ga Radionuclide Contribution to the Development of Imaging Agents for Infection and Inflammation

I Velikyan - Contrast Media & Molecular Imaging, 2018 - Wiley Online Library
During the last decade, the utilization of 68Ga for the development of imaging agents has
increased considerably with the leading position in the oncology. The imaging of infection …

Glucose-functionalized liposomes for reducing false positives in cancer diagnosis

C Tzror-Azankot, O Betzer, T Sadan, M Motiei… - ACS …, 2020 - ACS Publications
Fluorodeoxyglucose-positron emission tomography (18F-FDG-PET) is a powerful tool for
cancer detection, staging, and follow-up. However, 18F-FDG-PET imaging has high rates of …

64Cu-DOTA as a surrogate positron analog of Gd-DOTA for cardiac fibrosis detection with PET: pharmacokinetic study in a rat model of chronic MI

H Kim, SJ Lee, C Davies-Venn, JS Kim… - Nuclear medicine …, 2016 - journals.lww.com
Objectives The aim of this study was to investigate the pharmacokinetics of 64 Cu-DOTA (1,
4, 7, 10-azacyclododecane-N, N′, N′′, N′′′-tetraacetic acid), a positron surrogate …

68Ga-DOTA chelate, a novel imaging agent for assessment of myocardial perfusion and infarction detection in a rodent model

A Autio, S Uotila, M Kiugel, V Kytö, H Liljenbäck… - Journal of Nuclear …, 2020 - Springer
Background Magnetic resonance imaging (MRI) with Gadolinium 1, 4, 7, 10-
tetraazacyclododecane-N′, N ″, N′′′, N ″″-tetraacetic acid (Gd-DOTA) enables …

Contribution of perfusion to the 11C‐acetate signal in brown adipose tissue assessed by DCE‐MRI and 68Ga‐DOTA PET in a rat model

G Richard, C Noll, M Archambault… - Magnetic …, 2021 - Wiley Online Library
Purpose Determine if dynamic contrast enhanced (DCE)‐MRI and/or 68 gallium 1, 4, 7, 10‐
tetraazacyclododecane N, N′, N ″, N‴‐tretraacetic acid (68Ga‐DOTA) positron emission …

Assessment of regional pulmonary blood flow using 68Ga-DOTA PET

C Velasco, J Mateo, A Santos, A Mota-Cobian… - EJNMMI research, 2017 - Springer
Background In vivo determination of regional pulmonary blood flow (PBF) is a valuable tool
for the evaluation of many lung diseases. In this study, the use of 68 Ga-DOTA PET for the in …

Quantitative assessment of myocardial blood flow and extracellular volume fraction using 68Ga-DOTA-PET: a feasibility and validation study in large animals

C Velasco, A Mota-Cobián, RA Mota, J Pellico… - Journal of Nuclear …, 2020 - Elsevier
Background Here we evaluated the feasibility of PET with Gallium-68 (68 Ga)-labeled DOTA
for non-invasive assessment of myocardial blood flow (MBF) and extracellular volume …

Explicit measurement of multi-tracer arterial input function for PET imaging using blood sampling spectroscopy

C Velasco, A Mota-Cobián, J Mateo, S España - EJNMMI physics, 2020 - Springer
Background Conventional PET imaging has usually been limited to a single tracer per scan.
We propose a new technique for multi-tracer PET imaging that uses dynamic imaging and …

Pancreatic GLP-1r binding potential is reduced in insulin-resistant pigs

CH Malbert, A Chauvin, M Horowitz… - BMJ Open Diabetes …, 2020 - drc.bmj.com
Introduction The insulinotropic capacity of exogenous glucagon like peptide-1 (GLP-1) is
reduced in type 2 diabetes and the insulin-resistant obese. We have tested the hypothesis …