Detergent-free isolation of membrane proteins and strategies to study them in a near-native membrane environment

B Krishnarjuna, A Ramamoorthy - Biomolecules, 2022 - mdpi.com
Atomic-resolution structural studies of membrane-associated proteins and peptides in a
membrane environment are important to fully understand their biological function and the …

Model architectures for bacterial membranes

AB Carey, A Ashenden, I Köper - Biophysical reviews, 2022 - Springer
The complex composition of bacterial membranes has a significant impact on the
understanding of pathogen function and their development towards antibiotic resistance. In …

Extracellular electron transfer increases fermentation in lactic acid bacteria via a hybrid metabolism

S Tejedor-Sanz, ET Stevens, S Li, P Finnegan… - Elife, 2022 - elifesciences.org
Energy conservation in microorganisms is classically categorized into respiration and
fermentation; however, recent work shows some species can use mixed or alternative …

Peripheral membrane proteins: promising therapeutic targets across domains of life

DM Boes, A Godoy-Hernandez, DGG McMillan - Membranes, 2021 - mdpi.com
Membrane proteins can be classified into two main categories—integral and peripheral
membrane proteins—depending on the nature of their membrane interaction. Peripheral …

A review on enzyme complexes of electron transport chain from Mycobacterium tuberculosis as promising drug targets

P Anand, Y Akhter - International journal of biological macromolecules, 2022 - Elsevier
Energy metabolism is a universal process occurring in all life forms. In Mycobacterium
tuberculosis (Mtb), energy production is carried out in two possible ways, oxidative …

Molecular mechanisms of microbial transmembrane electron transfer of electrochemically active bacteria

X Xiao, HQ Yu - Current Opinion in Chemical Biology, 2020 - Elsevier
Electrochemically active bacteria (EAB) can release electrons generated by anaerobic
respiration to various electron acceptors in various bioelectrochemical systems via …

Organocatalyzed controlled copolymerization of perfluorinated vinyl ethers and unconjugated monomers driven by light

Q Quan, Y Zhao, K Chen, H Zhou, C Zhou… - ACS Catalysis, 2022 - ACS Publications
Perfluorinated vinyl ethers (PFVEs) are an important category of monomers for producing
fluoropolymers that have found broad applications. In this work, by developing a dibenzo [a …

A simple assay for inhibitors of mycobacterial oxidative phosphorylation

SA Harden, GM Courbon, Y Liang, AS Kim… - Journal of Biological …, 2024 - ASBMB
Oxidative phosphorylation, the combined activities of the electron transport chain (ETC) and
ATP synthase, has emerged as a valuable target for antibiotics to treat infection with …

[HTML][HTML] Tunable biomimetic bacterial membranes from binary and ternary lipid mixtures and their application in antimicrobial testing

E Krok, M Stephan, R Dimova, L Piatkowski - Biochimica et Biophysica Acta …, 2023 - Elsevier
The reconstruction of accurate yet simplified mimetic models of cell membranes is a very
challenging goal of synthetic biology. To date, most of the research focuses on the …

Proposed mechanisms for the extracellular release of PD-L1 by the anticancer saponin platycodin D

C Bailly, G Vergoten - International Immunopharmacology, 2020 - Elsevier
Platycodin D (PTD) is an oleanane-type terpenoid saponin, isolated from the plant
Platycodon grandiflorus. PTD displays multiple pharmacological effects, notably significant …