In the last decades, autoimmune diseases have experienced a dramatic increase in Western
countries. The involvement of environmental factors is strongly suspected to explain this rise …

Introduction The evidence from published studies on the association between obesity and
rheumatoid arthritis has been contradictory. To clarify the association between obesity and …

Objective Obesity is an underrecognized risk factor for rheumatoid arthritis (RA). In recent
years, both the prevalence of obesity and the incidence of RA have been rising. Our …

Background The etiology of male breast cancer is poorly understood, partly because of its
relative rarity. Although genetic factors are involved, less is known regarding the role of …

Objective: Whether adiposity and lack of physical activity affect the risk for developing
meningioma and glioma is poorly understood. Our objective was to characterize these …

This article is part of a Special Issue “Puberty and Adolescence”. Historical records reveal a
secular trend toward earlier onset of puberty in both males and females, often attributed to …

Introduction Morbidity/mortality is higher in men with below‐normal serum testosterone.
Restoring testosterone to normal is beneficial. Aim Assessment of safety and effectiveness of …

With expanding knowledge on the health benefits of exercise, there is an increasing
demand for information on the andrological consequences of participating in sports. These …

Background There are observational data suggesting an inverse association between
circulating concentrations of sex hormone binding globulin (SHBG) and risk of …

The prevalence of fusions of the transmembrane protease, serine 2, gene (TMPRSS2) with
the erythroblast transformation-specific–related gene (ERG), or TMPRSS2: ERG, in prostate …