• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Purpose Genetic testing has advanced significantly since the publication of the 2011
HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the …

The family of the human small Heat Shock Proteins (HSPBs) consists of ten members of
chaperones (HSPB1-HSPB10), characterized by a low molecular weight and capable of …

Genetic cardiomyopathies are disorders of the cardiac muscle, most often explained by
pathogenic mutations in genes encoding sarcomere, cytoskeleton, or ion channel proteins …

In the early nineties, few years before the birth of Europace, the clinical and scientific world
of familial arrhythmogenic conditions was revolutionized by the identification of the first …

The post-acute sequelae of COVID-19 (PASC), also known as long COVID, is often
associated with debilitating symptoms and adverse multisystem consequences. We obtain …

Background Dilated cardiomyopathy (DCM) is a life-threatening heart disease and a
common cause of heart failure due to systolic dysfunction and subsequent left or …

Background Dilated cardiomyopathy (DCM), characterized by progressive left ventricular
enlargement and systolic dysfunction, is the most common type of cardiomyopathy and a …

A polygenic risk score (PRS) is derived from a genome-wide association study and
represents an aggregate of thousands of single-nucleotide polymorphisms that provide a …

Here, we review the highlights of cardiovascular basic science published in 2021 and early
2022 on behalf of the European Society of Cardiology Council for Basic Cardiovascular …