[HTML][HTML] The interaction of human pathogenic fungi with C-type lectin receptors

S Goyal, JC Castrillón-Betancur, E Klaile… - Frontiers in …, 2018 - frontiersin.org
Fungi, usually present as commensals, are a major cause of opportunistic infections in
immunocompromised patients. Such infections, if not diagnosed or treated properly, can …

PAMPs of the fungal cell wall and mammalian PRRs

R Hatinguais, JA Willment, GD Brown - The Fungal Cell Wall: An Armour …, 2020 - Springer
Fungi are opportunistic pathogens that infect immunocompromised patients and are
responsible for an estimated 1.5 million deaths every year. The antifungal innate immune …

[HTML][HTML] During Aspergillus infection, monocyte-derived DCs, neutrophils, and plasmacytoid DCs enhance innate immune defense through CXCR3-dependent …

Y Guo, S Kasahara, A Jhingran, NL Tosini, B Zhai… - Cell host & …, 2020 - cell.com
Aspergillus fumigatus, a ubiquitous mold, is a common cause of invasive aspergillosis (IA) in
immunocompromised patients. Host defense against IA relies on lung-infiltrating neutrophils …

[HTML][HTML] Innate Immunity against Cryptococcus, from Recognition to Elimination

A Campuzano, FL Wormley Jr - Journal of fungi, 2018 - mdpi.com
Cryptococcus species, the etiological agents of cryptococcosis, are encapsulated fungal
yeasts that predominantly cause disease in immunocompromised individuals, and are …

Contact, collaboration, and conflict: signal integration of Syk-coupled C-type lectin receptors

J Ostrop, R Lang - The Journal of Immunology, 2017 - journals.aai.org
Several spleen tyrosine kinase–coupled C-type lectin receptors (CLRs) have emerged as
important pattern recognition receptors for infectious danger. Because encounter with …

[HTML][HTML] Animal Models of Cryptococcus neoformans in Identifying Immune Parameters Associated With Primary Infection and Reactivation of Latent Infection

TG Normile, AM Bryan, M Del Poeta - Frontiers in Immunology, 2020 - frontiersin.org
Cryptococcus species are environmental fungal pathogens and the causative agents of
cryptococcosis. Infection occurs upon inhalation of infectious particles, which proliferate in …

DectiSomes: C-type lectin receptor-targeted liposomes as pan-antifungal drugs

RB Meagher, ZA Lewis, S Ambati, X Lin - Advanced drug delivery reviews, 2023 - Elsevier
Combatting the ever-increasing threat from invasive fungal pathogens faces numerous
fundamental challenges, including constant human exposure to large reservoirs of species …

[HTML][HTML] Pulmonary Macrophage and Dendritic Cell Responses to Cryptococcus neoformans

BN Nelson, AN Hawkins, KL Wozniak - Frontiers in cellular and …, 2020 - frontiersin.org
The fungal pathogen Cryptococcus neoformans can cause life-threatening infections in
immune compromised individuals. This pathogen is typically acquired via inhalation, and …

[HTML][HTML] Cryptococcus escapes host immunity: What do we know?

C Yang, Y Huang, Y Zhou, X Zang, H Deng… - Frontiers in Cellular …, 2022 - frontiersin.org
Cryptococcus is an invasive fungus that seriously endangers human life and health, with a
complex and well-established immune-escaping mechanism that interferes with the function …

C-type lectin receptor-mediated immune recognition and response of the microbiota in the gut

TH Li, L Liu, YY Hou, SN Shen… - Gastroenterology …, 2019 - academic.oup.com
C-type lectin receptors (CLRs) are powerful pattern-recognition receptors that discern
'self'and 'non-self'in our body and protect us from invasive pathogens by mediating immune …