Recent advances in the transition-metal-free synthesis of quinoxalines

B Borah, LR Chowhan - RSC advances, 2021 - pubs.rsc.org
Quinoxalines, also known as benzo [a] pyrazines, constitute an important class of nitrogen-
containing heterocyclic compounds as a result of their widespread prevalence in natural …

Synthesis of functionalised isochromans: epoxides as aldehyde surrogates in hexafluoroisopropanol

C Muller, F Horký, M Vayer, A Golushko, D Lebœuf… - Chemical …, 2023 - pubs.rsc.org
The oxa-Pictet–Spengler reaction is arguably the most straightforward and modular way to
construct the privileged isochroman motif, but its scope is largely limited to benzaldehyde …

Ruthenium-catalyzed divergent deaminative and denitrative C–N cleavages: facile access to quinoxalines

S Liu, J Liang, P Zhang, Z Li, LY Jiao, W Jia… - Organic Chemistry …, 2023 - pubs.rsc.org
Divergent deaminative and denitrative C–N cleavages and cascade transformations using
amines and nitroalkanes have been developed under a highly effective and environmentally …

Iodine-promoted oxidative cyclization of acylated and alkylated derivatives from epoxides toward the synthesis of aza heterocycles

A Jayaram, K Govindan, VR Kannan… - The Journal of …, 2023 - ACS Publications
A new method for directly synthesizing acylated and alkylated quinazoline derivatives by the
epoxide ring-opening reaction in the presence of I2/DMSO with 2-aminobenzamide is …

Bifunctional acidic ionic liquid-catalyzed decarboxylative cascade synthesis of quinoxalines in water under ambient conditions

S Liu, P Zhang, Y Zhang, X Zhou, J Liang… - Organic Chemistry …, 2021 - pubs.rsc.org
An acid-functionalized ionic liquid (IL)-catalyzed cascade decarboxylative cyclization of 2-
arylanilines with α-oxocarboxylic acids was developed. This approach offered a sustainable …

PEG-400 as a carbon synthon: highly selective synthesis of quinolines and methylquinolines under metal-free conditions

C Ding, S Li, K Feng, C Ma - Green Chemistry, 2021 - pubs.rsc.org
A metal-free, peroxide-free, and efficient procedure for the highly selective synthesis of
quinolines and methylquinolines was reported. The main feature of this method was that the …

Efficient synthesis of pyrrolo [1, 2-α] quinoxalines mediated by ethyl 2-(4-nitrophenyl) azocarboxylate

DH Lee, GY Kim, J Kim - New Journal of Chemistry, 2023 - pubs.rsc.org
The synthesis of pyrrolo [1, 2-α] quinoxalines is of importance, because they possess a
variety of biological activities, and interesting fluorescence/photophysical properties …

Mo–Catalyzed One‐Pot Synthesis of N‐Polyheterocycles from Nitroarenes and Glycols with Recycling of the Waste Reduction Byproduct. Substituent‐Tuned …

R Hernández‐Ruiz, R Rubio‐Presa… - … A European Journal, 2021 - Wiley Online Library
A catalytic domino reduction–imine formation–intramolecular cyclization–oxidation for the
general synthesis of a wide variety of biologically relevant N‐polyheterocycles, such as …

Electrochemical oxidative dehydrogenative annulation of 1-(2-aminophenyl) pyrroles with cleavage of ethers to synthesize pyrrolo [1, 2-a] quinoxaline derivatives

F Sun, M Miao, W Li, XB Lan, JQ Yu… - Organic & Biomolecular …, 2024 - pubs.rsc.org
An array of pyrrolo [1, 2-a] quinoxaline derivatives were achieved with moderate to good
yields via the electrochemical redox reaction, which includes the functionalization of C (sp3) …

H2O2-Mediated Synthesis of a Quinazolin-4(3H)-one Scaffold: A Sustainable Approach

S Kumar, K Padala, B Maiti - ACS omega, 2023 - ACS Publications
A quinazolin-4 (3 H)-one ring system is a privileged heterocyclic moiety with distinctive
biological properties. From this perspective, the development of an efficient strategy for the …