The birth, evolution and death of metabolic gene clusters in fungi

A Rokas, JH Wisecaver, AL Lind - Nature Reviews Microbiology, 2018 - nature.com
Fungi contain a remarkable diversity of both primary and secondary metabolic pathways
involved in ecologically specialized or accessory functions. Genes in these pathways are …

Fungal gene cluster diversity and evolution

JC Slot - Advances in genetics, 2017 - Elsevier
Metabolic gene clusters (MGCs) have provided some of the earliest glimpses at the
biochemical machinery of yeast and filamentous fungi. MGCs encode diverse genetic …

Fungal adaptation to plant defences through convergent assembly of metabolic modules

E Gluck‐Thaler, V Vijayakumar, JC Slot - Molecular ecology, 2018 - Wiley Online Library
The ongoing diversification of plant defence compounds exerts dynamic selection pressures
on the microorganisms that colonize plant tissues. Evolutionary processes that generate …

Evidence of selection in the ectodysplasin pathway among endangered aquatic mammals

N Font-Porterias, MG McNelis, D Comas… - Integrative …, 2022 - academic.oup.com
The ectodysplasin pathway has been a target of evolution repeatedly. Genetic variation in
the key genes of this pathway (EDA, EDAR, and EDARADD) results in a rich source of …

Characterization and regulation of biosynthetic gene clusters in Aspergillus niger

G Evdokias - 2020 - spectrum.library.concordia.ca
Fungi produce a broad range of secondary metabolites with various bioactivities that have
allowed them to be used as antibiotics and pharmaceutical drugs. The genes encoding …