Poly (ethylene glycol) alternatives in biomedical applications

X Yao, C Qi, C Sun, F Huo, X Jiang - Nano Today, 2023 - Elsevier
Abstract Poly (ethylene glycol)(PEG) as gold standard has been extensively conjugated to
diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is …

Peptoids and polypeptoids at the frontier of supra-and macromolecular engineering

N Gangloff, J Ulbricht, T Lorson, H Schlaad… - Chemical …, 2016 - ACS Publications
In most general terms, polymers and their supramolecular assemblies have been defining
life on this planet since its conception. Polymers of nucleic acids carry the code of life and …

Polysarcosine-containing copolymers: Synthesis, characterization, self-assembly, and applications

A Birke, J Ling, M Barz - Progress in Polymer Science, 2018 - Elsevier
Although the first polysarcosine (pSar) synthesis by Wesseley et al. was reported almost a
century ago, it was only recently that pSar gained broader attention and is considered a …

Sequence programmable peptoid polymers for diverse materials applications

AS Knight, EY Zhou, MB Francis… - Advanced …, 2015 - Wiley Online Library
Polymer sequence programmability is required for the diverse structures and complex
properties that are achieved by native biological polymers, but efforts towards controlling the …

Polysarcosine as an alternative to PEG for therapeutic protein conjugation

Y Hu, Y Hou, H Wang, H Lu - Bioconjugate chemistry, 2018 - ACS Publications
The performance of many therapeutic proteins, including human interferon-α2b (IFN), is
often impeded by their intrinsic instability to protease, poor pharmacokinetics, and strong …

Polypeptoid polymers: Synthesis, characterization, and properties

BA Chan, S Xuan, A Li, JM Simpson… - Polymers for …, 2017 - Wiley Online Library
Polypeptoids, a class of peptidomimetic polymers, have emerged at the forefront of
macromolecular and supramolecular science and engineering as the technological …

Poly (α‐Peptoid) s Revisited: Synthesis, Properties, and Use as Biomaterial

C Secker, SM Brosnan, R Luxenhofer… - Macromolecular …, 2015 - Wiley Online Library
Polypeptoids have been of great interest in the polymer science community since the early
half of the last century; however, they had been basically forgotten materials until the last …

Biodegradable polysarcosine with inserted alanine residues: Synthesis and enzymolysis

P Zhou, T Shen, W Chen, J Sun, J Ling - Biomacromolecules, 2022 - ACS Publications
Polysarcosine (PSar), a water-soluble polypeptoid, is gifted with biodegradability via the
random ring-opening copolymerization of sarcosine-and alanine-N-thiocarboxyanhydrides …

Controlled Polymerization of N-Substituted Glycine N-Thiocarboxyanhydrides Initiated by Rare Earth Borohydrides toward Hydrophilic and Hydrophobic Polypeptoids

X Tao, Y Deng, Z Shen, J Ling - Macromolecules, 2014 - ACS Publications
N-substituted glycine N-thiocarboxyanhydrides (NTAs) are alternative monomers to prepare
polypeptoids with large-scale producing potential compared to the corresponding N …

Polysarcosine brush stabilized gold nanorods for in vivo near-infrared photothermal tumor therapy

H Zhu, Y Chen, FJ Yan, J Chen, XF Tao, J Ling, B Yang… - Acta biomaterialia, 2017 - Elsevier
Gold nanorods (AuNRs) are suitable candidates for photothermal therapy in vivo, because
of their excellent ability to transfer near-infrared (NIR) light into heat. However, appropriate …