Abstract Cyclic GMP–AMP synthase (cGAS) is a cytosolic DNA sensor that produces the
second messenger cG [2′–5′] pA [3′–5′] p (2′ 3′-cGAMP) and controls activation of …

Cytoskeleton proteins have been long recognized as structural proteins that provide the
necessary mechanical architecture for cell development and tissue homeostasis. With the …

Identifying genetic variants that are associated with variation in DNA methylation, an
analysis commonly referred to as methylation quantitative trait locus (meQTL) mapping, is an …

Abstract cGAS/DncV-like nucleotidyltransferase (CD-NTase) family members are immune
sensors that synthesize diverse nucleotide signals to initiate antiviral response in bacteria …

Phakomatosis pigmentovascularis is a diagnosis that denotes the coexistence of pigmentary
and vascular birthmarks of specific types, accompanied by variable multisystem …

Exposure to ambient air pollution during pregnancy has been associated with an increased
risk of preeclampsia (PE). Some suggested mechanisms behind this association are …

Background: Non–small cell lung cancer (NSCLC) is highly malignant with driver somatic
mutations and genomic instability. Long non-coding RNAs (lncRNAs) play a vital role in …

Simple Summary Radiotherapy for cancer patients can cause abnormal DNA methylation.
We developed a computational workflow that can identify crucial methylation alterations …

Background Primary hepatoid adenocarcinoma of the gallbladder is a relatively rare type of
extrahepatic adenocarcinoma. The genetic changes involved in this type of adenocarcinoma …

The molecular detection of pathogen infection and subsequent initiation of an immune
response is an essential function of cellular life. Animals encode innate immune proteins …