Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

Polypeptides have attracted considerable attention in recent decades due to their inherent
biodegradability and tunable cytocompatibility. Macromolecular design in conjunction with …

Synthetic polypeptides from the ring-opening polymerization of N-carboxyanhydrides
(NCAs) are one of the most important biomaterials. The unique features of these synthetic …

Poly (α-L-glutamic acid)(PGA) is a class of synthetic polypeptides composed of the
monomeric unit α-L-glutamic acid. Owing to their biocompatibility, biodegradability, and non …

Polypeptides have the same or similar backbone structures as proteins and peptides,
rendering them as suitable and important biomaterials. Amino acid N-carboxyanhydrides …

Reported here is the first aqueous ring‐opening polymerization (ROP) of N‐
carboxyanhydrides (NCAs) using α‐amino‐poly (ethylene oxide) as a macroinitiator to …

A great hurdle in the production of synthetic polypeptides lies in the access of N-
carboxyanhydrides (NCA) monomers, which requires dry solvents, Schlenk line/gloveboxe …

Complex coacervate microdroplets are finding increased utility in synthetic cell applications
due to their cytomimetic properties. However, their intrinsic membrane-free nature results in …

Although the first polysarcosine (pSar) synthesis by Wesseley et al. was reported almost a
century ago, it was only recently that pSar gained broader attention and is considered a …

Polypeptides have broad applications and can be prepared via ring-opening polymerization
of α-amino acid N-carboxyanhydrides (NCAs). Conventional initiators, such as primary …