Mechanotransduction refers to the conversion of mechanical forces into biochemical or
electrical signals that initiate structural and functional remodeling in cells and tissues. The …

Embryogenesis is a highly complex and dynamic process, and its visualization is crucial for
understanding basic physiological processes during development and for identifying and …

Blood flow and mechanical forces in the ventricle are implicated in cardiac development and
trabeculation. However, the mechanisms of mechanotransduction remain elusive. This is …

Heart development is topographically complex and requires visualization to understand its
progression. No comprehensive 3-dimensional primer of human cardiac development is …

The heart is the first functional organ in a developing embryo. Cardiac development
continues throughout developmental stages while the heart goes through a serious of …

With the explosion of gene editing tools in recent years, there has been a much greater
demand for mouse embryo phenotyping, and traditional methods such as histology and …

The role of hemodynamics in cardiovascular development is not well understood. Indeed, it
would be remarkable if it were, given the dauntingly complex array of intricately …

Application of optical imaging in developmental biology marks an exciting frontier in
biomedical optics. Optical resolution and imaging depth allow for investigation of growing …

Myocardial contractility and blood flow provide essential mechanical cues for the
morphogenesis of the heart. In general, endothelial cells change their migratory behavior in …

The chorioallantoic membrane (CAM) of the avian embryo is an intrinsically interesting gas
exchange and osmoregulation organ. Beyond study by comparative biologists, however, the …