TRPV4: molecular conductor of a diverse orchestra
Transient receptor potential vanilloid type 4 (TRPV4) is a calcium-permeable nonselective
cation channel, originally described in 2000 by research teams led by Schultz (Nat Cell Biol …
cation channel, originally described in 2000 by research teams led by Schultz (Nat Cell Biol …
TRPV3: Structure, diseases and modulators
W Su, X Qiao, W Wang, S He, K Liang, X Hong - Molecules, 2023 - mdpi.com
Transient receptor potential vanillin 3 (TRPV3) is a member of the transient receptor
potential (TRP) superfamily. As a Ca2+-permeable nonselective cation channel, TRPV3 can …
potential (TRP) superfamily. As a Ca2+-permeable nonselective cation channel, TRPV3 can …
Thermosensation involving thermo-TRPs
M Kashio - Molecular and cellular endocrinology, 2021 - Elsevier
The transient receptor potential (TRP) channels constitute a superfamily of large ion
channels that are activated by a wide range of chemical, mechanical and thermal stimuli …
channels that are activated by a wide range of chemical, mechanical and thermal stimuli …
The role of TRPV4 in fibrosis
L Zhan, J Li - Gene, 2018 - Elsevier
The transient receptor potential vanilloid 4 (TRPV4) is a highly Ca 2+-permeable non-
selective cation channel in TRPV family. Accumulating evidence hints that TRPV4 play a …
selective cation channel in TRPV family. Accumulating evidence hints that TRPV4 play a …
The TRPM2 channel: A thermo-sensitive metabolic sensor
M Kashio, M Tominaga - Channels, 2017 - Taylor & Francis
Living organisms continually experience changes in ambient temperature. To detect such
temperature changes for adaptive behavioral responses, we evolved the ability to sense …
temperature changes for adaptive behavioral responses, we evolved the ability to sense …
Skin matters! The role of keratinocytes in nociception: a rational argument for the development of topical analgesics
JM Keppel Hesselink, DJ Kopsky… - Journal of pain …, 2016 - Taylor & Francis
Treatment of neuropathic pain using topical formulations is still in its infancy. Only few topical
analgesic formulations have become available for clinical use, and among these, analgesic …
analgesic formulations have become available for clinical use, and among these, analgesic …
Imaging photoplethysmography for clinical assessment of cutaneous microcirculation at two different depths
Z Marcinkevics, U Rubins, J Zaharans… - Journal of …, 2016 - spiedigitallibrary.org
The feasibility of bispectral imaging photoplethysmography (iPPG) system for clinical
assessment of cutaneous microcirculation at two different depths is proposed. The iPPG …
assessment of cutaneous microcirculation at two different depths is proposed. The iPPG …
Nicotinamide is an endogenous agonist for a C. elegans TRPV OSM-9 and OCR-4 channel
TRPV ion channels are directly activated by sensory stimuli and participate in thermo-,
mechano-and chemo-sensation. They are also hypothesized to respond to endogenous …
mechano-and chemo-sensation. They are also hypothesized to respond to endogenous …
Nicotinic acid suppresses sebaceous lipogenesis of human sebocytes via activating hydroxycarboxylic acid receptor 2 (HCA2)
A Markovics, KF Tóth, KE Sós, J Magi… - Journal of Cellular …, 2019 - Wiley Online Library
Nicotinic acid (NA) activates hydroxycarboxylic acid receptor 2 (HCA2), and it is widely used
in treating dyslipidaemias. Since its side effects include skin dryness, whereas its deficiency …
in treating dyslipidaemias. Since its side effects include skin dryness, whereas its deficiency …
Novel derivatives of nicotinic acid as promising anticancer agents
Background: Cancer has become the second leading cause of death worldwide. Despite of
the availability of significant number of anticancer agents, cancer is still incurable especially …
the availability of significant number of anticancer agents, cancer is still incurable especially …