Recently, deep learning frameworks have rapidly become the main methodology for
analyzing medical images. Due to their powerful learning ability and advantages in dealing …

Background The objective of this systematic review and meta-analysis was to determine the
prognostic value of total tumor-infiltrating lymphocytes (TILs) and subtypes of TILs (CD4+ …

PURPOSE To update recommendations on appropriate use of breast cancer biomarker
assay results to guide adjuvant endocrine and chemotherapy decisions in early-stage breast …

Purpose The aim of the current study was to conduct a pooled analysis of studies that have
investigated the prognostic value of tumor-infiltrating lymphocytes (TILs) in early-stage triple …

Tumors develop multiple mechanisms of immune evasion as they progress, with some
cancer types being inherently better at 'hiding'than others. With an increased understanding …

Background Whether tumour-infiltrating lymphocytes (TILs) play different roles in different
molecular subtypes of breast cancer remains unknown. Additionally, their prognostic and …

Studies have shown that the presence of tumor infiltrating lymphocytes (TILs) in Triple
Negative Breast Cancer (TNBC) is associated with better prognosis. However, the molecular …

Inflammation is now recognized as a hallmark of cancer. Genetic changes in the cancer cell
are accepted as the match that lights the fire, whilst inflammation is seen as the fuel that …

Immunoediting represents a complex and dynamic process involving cancer and immune
system cells, composed by three intertwined phases: elimination, equilibrium and escape. A …

Breast cancer has not previously been considered a highly immunogenic cancer.
Observations of tumour-infiltrating lymphocytes (TILs) in and around neoplastic cells in …