Brugada syndrome (BrS) is diagnosed by a coved-type ST-segment elevation in the right
precordial leads on the electrocardiogram (ECG), and it is associated with an increased risk …

Although sudden cardiac death (SCD) is one of the most important modes of death in
Western countries, pathologists and public health physicians have not given this problem …

Brugada syndrome (BrS) was first described in 1992 as an aberrant pattern of ST segment
elevation in right precordial leads with a high incidence of sudden cardiac death (SCD) in …

Pediatric cardiomyopathies (CMs) and electrical diseases constitute a heterogeneous
spectrum of disorders distinguished by structural and electrical abnormalities in the heart …

BACKGROUND: A pathogenic/likely pathogenic variant can be found in 20% to 25% of
patients with Brugada syndrome (BrS) and a pathogenic/likely pathogenic variant in SCN5A …

Aims A pathogenic/likely pathogenic (P/LP) variant in SCN5A is found in 20–25% of patients
with Brugada syndrome (BrS). However, the diagnostic yield and prognosis of gene panel …

Abstract The Human Genome Project (HGP), as the primary sequencing of the human
genome, lasted more than one decade to be completed using the traditional Sanger's …

Brugada syndrome (BrS) is a hereditary disorder, characterized by a specific
electrocardiogram pattern and highly related to an increased risk of sudden cardiac death …

Plakophilin-2 (PKP2) is a component of the desmosome complex and known for its role in
cell-cell adhesion. Recently, alterations in the Pkp2 gene have been associated with …

Aims Coronary artery disease accounts for the majority of sudden cardiac deaths (SCD) in
the older population whereas cardiomyopathies and arrhythmogenic abnormalities …