Global HIV neurology: a comprehensive review
Neurological conditions associated with HIV remain major contributors to morbidity and
mortality and are increasingly recognized in the aging population on long-standing …
mortality and are increasingly recognized in the aging population on long-standing …
The CCL2/CCR2 axis in the pathogenesis of HIV-1 infection: a new cellular target for therapy?
D Angela Covino, M Sabbatucci… - Current drug targets, 2016 - ingentaconnect.com
The identification of chemokine receptors as necessary co-receptors for HIV entry into target
cells represented a breakthrough in the understanding of the pathogenesis of this viral …
cells represented a breakthrough in the understanding of the pathogenesis of this viral …
Blood-brain barrier disruption is initiated during primary HIV infection and not rapidly altered by antiretroviral therapy
E Rahimy, FY Li, L Hagberg, D Fuchs… - The Journal of …, 2017 - academic.oup.com
Background. We explored the establishment of abnormal blood-brain barrier (BBB)
permeability and its relationship to neuropathogenesis during primary human …
permeability and its relationship to neuropathogenesis during primary human …
Neurologic signs and symptoms frequently manifest in acute HIV infection
J Hellmuth, JLK Fletcher, V Valcour, E Kroon… - Neurology, 2016 - AAN Enterprises
Objective: To determine the incidence, timing, and severity of neurologic findings in acute
HIV infection (pre–antibody seroconversion), as well as persistence with combination …
HIV infection (pre–antibody seroconversion), as well as persistence with combination …
Acute retroviral syndrome is associated with high viral burden, CD4 depletion, and immune activation in systemic and tissue compartments
TA Crowell, DJ Colby, S Pinyakorn… - Clinical Infectious …, 2018 - academic.oup.com
Background Many individuals with acute human immunodeficiency virus infection (AHI)
experience acute retroviral syndrome (ARS), which is associated with adverse long-term …
experience acute retroviral syndrome (ARS), which is associated with adverse long-term …
HIV neuropathy
M Kaku, DM Simpson - Current opinion in HIV and AIDS, 2014 - journals.lww.com
The prevalence of those affected by HIV-DSP will continue to grow with the aging population
of HIV-infected individuals. Compared to the diabetic neuropathy drug trials, trials in both …
of HIV-infected individuals. Compared to the diabetic neuropathy drug trials, trials in both …
[HTML][HTML] The role of T-lymphocytes in neuropathic pain initiation, development of chronicity and treatment
DA Galvin, C McCrory - Brain, Behavior, & Immunity-Health, 2021 - Elsevier
Ongoing research has strongly suggested the role the immune system plays in the
pathogenesis of neuropathic pain. T cells appear to be one of the main regulators of the …
pathogenesis of neuropathic pain. T cells appear to be one of the main regulators of the …
[HTML][HTML] Kynurenine, tetrahydrobiopterin, and cytokine inflammatory biomarkers in individuals affected by diabetic neuropathic pain
Neuropathic pain is a common complication of diabetes with high morbidity and poor
treatment outcomes. Accumulating evidence suggests the immune system is involved in the …
treatment outcomes. Accumulating evidence suggests the immune system is involved in the …
[HTML][HTML] Reduced intraepidermal nerve fibre density, glial activation, and sensory changes in HIV type-1 Tat-expressing female mice: involvement of Tat during early …
Results: Intraepidermal nerve fibre density was significantly reduced after 6 weeks of Tat
induction, similar to sensory neuropathy seen in clinical HIV infection. Tat induction through …
induction, similar to sensory neuropathy seen in clinical HIV infection. Tat induction through …
Neurologic sequelae of primary HIV infection
Primary human immunodeficiency virus type 1 (HIV-1) infection is defined as the period from
initial infection with HIV to complete seroconversion. Neurologic sequelae of primary HIV-1 …
initial infection with HIV to complete seroconversion. Neurologic sequelae of primary HIV-1 …