Adverse childhood experiences (ACEs) may be referred to by other terms (eg, early life
adversity or stress and childhood trauma) and have a lifelong impact on mental and physical …

Abstract Introduction Neuromyelitis Optica (NMO) is an autoimmune inflammatory
demyelinating disease of the central nervous system (CNS) which predominantly involves …

Connective tissue diseases (CTDs) such as systemic lupus erythematosus, systemic
sclerosis, myositis, Sjögren's syndrome, and rheumatoid arthritis are systemic diseases …

Sjögren's syndrome (SjS) is a systemic autoimmune disease that mainly affects the exocrine
glands, leading to generalized mucosal dryness. However, primary SjS may initially present …

Purpose To elucidate the clinical and epidemiologic characteristics of optic neuritis in Japan.
Design Multicenter cross-sectional, observational cohort study. Participants A total of 531 …

Opinion statement Purpose of review Neurologic disease is a common extraglandular
manifestation of Sjögren's syndrome (SS), the study of which has been hampered both by …

Abstract Background Primary Sjögren's syndrome (SS) is a chronic systemic autoimmune
disease with varied neurological manifestations. SS is associated with anti-aquaporin-4 …

The aim of the present study was to analyze the clinical characteristics of primary Sjogren's
syndrome (pSS) with neuromyelitis optica spectrum disorder (NMOSD). We retrospectively …

In neuromyelitis optica spectrum disorders (NMOSD), the clinical and long-term prognostic
value of antinuclear antibodies (ANAs) is unclear. We analyzed registry data of NMO-IgG …

Case 7-2024: A 67-Year-Old Woman with Alternating Sixth Cranial Nerve Palsy | New England
Journal of Medicine Skip to main content The New England Journal of Medicine homepage …