Radiotherapy treatment for lung cancer: Current status and future directions

SK Vinod, E Hau - Respirology, 2020 - Wiley Online Library
Radiotherapy is an important modality used for the treatment of lung cancer. Seventy‐seven
percent of all patients with lung cancer have an evidence‐based indication for radiotherapy …

Small-cell lung cancer

JP Van Meerbeeck, DA Fennell, DKM De Ruysscher - The Lancet, 2011 - thelancet.com
The incidence and mortality of small-cell lung cancer worldwide make this disease a notable
health-care issue. Diagnosis relies on histology, with the use of immunohistochemical …

Small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up☆

AMC Dingemans, M Früh, A Ardizzoni… - Annals of …, 2021 - annalsofoncology.org
Small-cell lung cancer (SCLC) is the most aggressive form of lung cancer. Although SCLC is
characterised by rapid responses to chemotherapy (ChT) and sensitivity to radiotherapy …

Preservation of memory with conformal avoidance of the hippocampal neural stem-cell compartment during whole-brain radiotherapy for brain metastases (RTOG …

V Gondi, SL Pugh, WA Tome, C Caine… - Journal of Clinical …, 2014 - ascopubs.org
Purpose Hippocampal neural stem-cell injury during whole-brain radiotherapy (WBRT) may
play a role in memory decline. Intensity-modulated radiotherapy can be used to avoid …

Randomized phase III trial of prophylactic cranial irradiation with or without hippocampal avoidance for small-cell lung cancer (PREMER): a GICOR-GOECP-SEOR …

N Rodríguez de Dios, F Couñago… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Radiation dose received by the neural stem cells of the hippocampus during
whole-brain radiotherapy has been associated with neurocognitive decline. The key …

Memantine for the prevention of cognitive dysfunction in patients receiving whole-brain radiotherapy: a randomized, double-blind, placebo-controlled trial

PD Brown, S Pugh, NN Laack, JS Wefel… - Neuro …, 2013 - academic.oup.com
Background To determine the protective effects of memantine on cognitive function in
patients receiving whole-brain radiotherapy (WBRT). Methods Adult patients with brain …

Small cell lung cancer, version 2.2022, NCCN clinical practice guidelines in oncology

AKP Ganti, BW Loo, M Bassetti, C Blakely… - Journal of the National …, 2021 - jnccn.org
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Small Cell Lung
Cancer (SCLC) provide recommended management for patients with SCLC, including …

Small-cell lung cancer (SCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

M Früh, D De Ruysscher, S Popat, L Crinò… - Annals of …, 2013 - annalsofoncology.org
An estimated 1.6 million new lung cancers are diagnosed worldwide each year. The highest
incidence rates in males are observed in Central/Eastern and Southern Europe (57 and 49 …

Radiation therapy for small cell lung cancer: an ASTRO clinical practice guideline

CB Simone II, JA Bogart, AR Cabrera, ME Daly… - Practical radiation …, 2020 - Elsevier
Purpose Several sentinel phase III randomized trials have recently been published
challenging traditional radiation therapy (RT) practices for small cell lung cancer (SCLC) …

[HTML][HTML] Phase 3 randomized trial of prophylactic cranial irradiation with or without hippocampus avoidance in SCLC (NCT01780675)

JSA Belderbos, DKM De Ruysscher… - Journal of Thoracic …, 2021 - Elsevier
Introduction To compare neurocognitive functioning in patients with SCLC who received
prophylactic cranial irradiation (PCI) with or without hippocampus avoidance (HA). Methods …