Autism is a heterogeneous syndrome defined by impairments in three core domains: social
interaction, language and range of interests. Recent work has led to the identification of …

This article introduces the reader to the genetics of schizophrenia: its background; the status
of a variety of genetic findings; new developments (which are many since the last review) 1; …

Schizophrenia, a devastating psychiatric disorder, has a prevalence of 0.5–1%, with high
heritability (80–85%) and complex transmission. Recent studies implicate rare, large, high …

Twin and family studies in autistic disorders (AD) have elucidated a high heritability of the
narrow and broad phenotype of AD. In this review on the genetics of AD, we will initially …

Brachydactyly mental retardation syndrome (BDMR) is associated with a deletion involving
chromosome 2q37. BDMR presents with a range of features, including intellectual …

Gene families are groups of homologous genes that are likely to have highly similar
functions. Differences in family size due to lineage-specific gene duplication and gene loss …

Abstract Background Autism spectrum disorders (ASDs) comprise a range of
neurodevelopmental conditions of varying severity, characterized by marked qualitative …

The work conducted using genome-wide approaches during the past several years has
invigorated the field, and represents the dawn of molecular genetics of schizophrenia. The …

Autism is a heterogeneous neurodevelopmental disorder with a variety of different
etiologies, but with a heritability estimate of more than 90%. Although the strong correlation …

Autism spectrum disorders (ASDs) are a clinically complex group of childhood disorders that
have firm evidence of an underlying genetic etiology. Many techniques have been used to …