[HTML][HTML] Advantages and challenges of microfluidic cell culture in polydimethylsiloxane devices
Culture of cells using various microfluidic devices is becoming more common within
experimental cell biology. At the same time, a technological radiation of microfluidic cell …
experimental cell biology. At the same time, a technological radiation of microfluidic cell …
[PDF][PDF] Stem cell models of human brain development
I Kelava, MA Lancaster - Cell stem cell, 2016 - cell.com
Recent breakthroughs in pluripotent stem cell technologies have enabled a new class of in
vitro systems for functional modeling of human brain development. These advances, in …
vitro systems for functional modeling of human brain development. These advances, in …
[HTML][HTML] Recent advances in microfluidic technologies for cell-to-cell interaction studies
Microfluidic cell cultures are ideally positioned to become the next generation of in vitro
diagnostic tools for biomedical research, where key biological processes such as cell …
diagnostic tools for biomedical research, where key biological processes such as cell …
An atlas of nano-enabled neural interfaces
H Acarón Ledesma, X Li, JL Carvalho-de-Souza… - Nature …, 2019 - nature.com
Advances in microscopy and molecular strategies have allowed researchers to gain insight
into the intricate organization of the mammalian brain and the roles that neurons play in …
into the intricate organization of the mammalian brain and the roles that neurons play in …
Mechanical properties of cell sheets and spheroids: the link between single cells and complex tissues
YM Efremov, IM Zurina, VS Presniakova… - Biophysical …, 2021 - Springer
Cell aggregates, including sheets and spheroids, represent a simple yet powerful model
system to study both biochemical and biophysical intercellular interactions. However, it is …
system to study both biochemical and biophysical intercellular interactions. However, it is …
Microfluidics for neuronal cell and circuit engineering
The widespread adoption of microfluidic devices among the neuroscience and neurobiology
communities has enabled addressing a broad range of questions at the molecular, cellular …
communities has enabled addressing a broad range of questions at the molecular, cellular …
[HTML][HTML] Functional characterization of human pluripotent stem cell-derived models of the brain with microelectrode arrays
A Pelkonen, C Pistono, P Klecki, M Gómez-Budia… - Cells, 2021 - mdpi.com
Human pluripotent stem cell (hPSC)-derived neuron cultures have emerged as models of
electrical activity in the human brain. Microelectrode arrays (MEAs) measure changes in the …
electrical activity in the human brain. Microelectrode arrays (MEAs) measure changes in the …
Compartmentalized microfluidic platforms: the unrivaled breakthrough of in vitro tools for neurobiological research
E Neto, L Leitão, DM Sousa, CJ Alves… - Journal of …, 2016 - Soc Neuroscience
Microfluidic technology has become a valuable tool to the scientific community, allowing
researchers to study fine cellular mechanisms with higher variable control compared with …
researchers to study fine cellular mechanisms with higher variable control compared with …
Integration of reconfigurable microchannels into aligned three-dimensional neural networks for spatially controllable neuromodulation
Anisotropically organized neural networks are indispensable routes for functional
connectivity in the brain, which remains largely unknown. While prevailing animal models …
connectivity in the brain, which remains largely unknown. While prevailing animal models …
[HTML][HTML] Functional bioengineered models of the central nervous system
The functional complexity of the central nervous system (CNS) is unparalleled in living
organisms. Its nested cells, circuits and networks encode memories, move bodies and …
organisms. Its nested cells, circuits and networks encode memories, move bodies and …