Overview of chemotherapy for Gastric Cancer

Y Sato, K Okamoto, Y Kida, Y Mitsui, Y Kawano… - Journal of Clinical …, 2023 - mdpi.com
Gastric cancer (GC) is one of the most clinically challenging cancers worldwide. Over the
past few years, new molecular-targeted agents and immunotherapy have markedly …

Harnessing DNA replication stress for novel cancer therapy

H Zhu, U Swami, R Preet, J Zhang - Genes, 2020 - mdpi.com
DNA replication is the fundamental process for accurate duplication and transfer of genetic
information. Its fidelity is under constant stress from endogenous and exogenous factors …

EphA2‐to‐YAP pathway drives gastric cancer growth and therapy resistance

C Huang, W Yuan, C Lai, S Zhong… - … Journal of Cancer, 2020 - Wiley Online Library
Yes‐associated protein (YAP) is a transcriptional coactivator that promotes cell proliferation,
stem cell maintenance and tissue homeostasis. The YAP activity is primarily regulated …

PINTology: A short history of the lncRNA LINC‐PINT in different diseases

I Bukhari, MR Khan, MA Hussain… - Wiley …, 2022 - Wiley Online Library
LINC‐PINT is a p53‐induced long intergenic noncoding transcript that plays a crucial role in
many diseases, especially cancer. This long noncoding RNA (lncRNA) gene produces in …

Roles of Nrf2 in gastric cancer: Targeting for therapeutic strategies

T Farkhondeh, AM Pourbagher-Shahri… - Molecules, 2021 - mdpi.com
Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) is a specific transcription factor with
potent effects on the regulation of antioxidant gene expression that modulates cell …

[HTML][HTML] Strategy for improved therapeutic efficiency of curcumin in the treatment of gastric cancer

M Jakubek, Z Kejík, R Kaplanek, R Hromadka… - Biomedicine & …, 2019 - Elsevier
Gastric cancer is a common oncological disease. Although enormous efforts have been
expended, possible therapeutic modalities are still limited. For this reason, new therapeutic …

Development and evaluation of a new gastroretentive drug delivery system: Nanomicelles-loaded floating mucoadhesive beads

N Chen, Q Li, J Li, Y Ren, G Wu, Y Liu, Y Shi - Journal of Drug Delivery …, 2019 - Elsevier
To better treat gastric diseases and lower systemic side effect, it is essential to design new
vectors to control drug release in stomach. Aiming to this challenge, we developed a new …

Patterns of recurrence after curative D2 resection for gastric cancer: Implications for postoperative radiotherapy

J Xu, L Shen, Y Shui, W Yu, Q Guo, R Yu… - Cancer …, 2020 - Wiley Online Library
Background High‐quality randomized controlled trials have demonstrated the benefit of
radiotherapy (RT) in patients with radical resected gastric cancer (GC), however, utilization …

Is there still a place for radiotherapy in gastric cancer?

IY Chong, I Chau - Current Opinion in Pharmacology, 2023 - Elsevier
Stomach cancer is an aggressive disease and represents a global health problem. The
majority of patients with localised disease present with locally advanced cancer that requires …

Cascades between miRNAs, lncRNAs and the NF‑κB signaling pathway in gastric cancer

R Chen, M Yang, W Huang… - Experimental and …, 2021 - spandidos-publications.com
Gastric cancer is a common digestive tract malignancy that is mainly treated with surgery
combined with perioperative adjuvant chemoradiotherapy and biological targeted therapy …