The optimal performance of the cardiovascular system, as well as the break-down of this
performance with disease, both involve complex biomechanical interactions between the …

Abstract Purpose of Review Arterial pulse waveform analysis has a long tradition but has not
pervaded medical routine yet. This review aims to answer the question whether the …

Background The effects of monthly, high‐dose, long‐term (≥ 1‐year) vitamin D
supplementation on central blood pressure (BP) parameters are unknown. Methods and …

Wave separation analysis and wave intensity analysis (WIA) use (aortic) pressure and flow
to separate them in their forward and backward (reflected) waves. While wave separation …

Excess pressure integral (XSPI), a new index of surplus work performed by the left ventricle,
can be calculated from blood pressure waveforms and may indicate circulatory dysfunction …

Several morphological parameters based on the central aortic pressure waveform are
proposed as cardiovascular risk markers, yet no study has definitively demonstrated the …

It is well accepted that angiotensin II (Ang II) induces altered vascular stiffness through
responses including both structural and material remodeling. Concurrent with remodeling is …

Flow-mediated skin fluorescence (FMSF) at 460 nm is a non-invasive method for assessing
dynamic changes in the reduced form of nicotinamide adenine dinucleotide (NADH) and …

Background Numerous mechanical biomarkers derived from pulse wave analysis (PWA)
have been proposed to predict cardiovascular outcomes. However, whether these …

Pressure and flow are travelling waves and are reflected at many locations. The forward and
reflected waves, obtained by wave separation, are compound waves. This compounded …