Homocysteine–from disease biomarker to disease prevention

AD Smith, H Refsum - Journal of internal medicine, 2021 - Wiley Online Library
We have reviewed the literature and have identified more than 100 diseases or conditions
that are associated with raised concentrations of plasma total homocysteine. The …

Recent advances in neuropathology, biomarkers and therapeutic approach of multiple system atrophy

S Koga, DW Dickson - Journal of Neurology, Neurosurgery & …, 2018 - jnnp.bmj.com
Multiple system atrophy (MSA) is a progressive neurodegenerative disorder characterised
by a variable combination of autonomic failure, levodopa-unresponsive parkinsonism …

[HTML][HTML] Accuracy improvement for predicting Parkinson's disease progression

M Nilashi, O Ibrahim, A Ahani - Scientific reports, 2016 - nature.com
Parkinson's disease (PD) is a member of a larger group of neuromotor diseases marked by
the progressive death of dopamineproducing cells in the brain. Providing computational …

The evolving role of neuro‐immune interaction in brain repair after cerebral ischemic stroke

X Wang, W Xuan, ZY Zhu, Y Li, H Zhu… - CNS neuroscience & …, 2018 - Wiley Online Library
Stroke is the world's leading cause of disability with limited brain repair treatments which
effectively improve long‐term neurological deficits. The neuroinflammatory responses …

Targeting the Wnt/β-catenin pathway in neurodegenerative diseases: recent approaches and current challenges

A Serafino, D Giovannini, S Rossi… - Expert Opinion on Drug …, 2020 - Taylor & Francis
Introduction Wnt/β-catenin signaling is an evolutionarily conserved pathway having a crucial
role in embryonic and adult life. Specifically, the Wnt/β-catenin axis is pivotal to the …

[HTML][HTML] Vitamin D, homocysteine, and folate in subcortical vascular dementia and Alzheimer dementia

R Moretti, P Caruso, M Dal Ben, C Conti… - Frontiers in aging …, 2017 - frontiersin.org
Dementia is a worldwide health problem which affects millions of patients; Alzheimer's
disease (AD) and subcortical vascular dementia (sVAD) are the two most frequent forms of …

[HTML][HTML] Neuroinflammation in multiple system atrophy: response to and cause of α-synuclein aggregation

BDM Vieira, RA Radford, RS Chung… - Frontiers in cellular …, 2015 - frontiersin.org
Multiple system atrophy (MSA) is a progressive neurodegenerative disease presenting with
combinations of autonomic dysfunction, parkinsonism, cerebellar ataxia and/or pyramidal …

Homocysteine and cognition: A systematic review of 111 studies

E Setién-Suero, M Suárez-Pinilla… - Neuroscience & …, 2016 - Elsevier
Background Elevated plasma homocysteine​​(Hcy) levels have been associated with
cognitive dysfunction in a wide range of conditions. The aim of this review is to establish …

Identifying the presence of Parkinson's disease using low-frequency fluctuations in BOLD signals

Y Tang, LI Meng, C Wan, Z Liu, W Liao, X Yan… - Neuroscience …, 2017 - Elsevier
Parkinson's disease (PD) is a chronic, progressive, and degenerative neurological disorder
that is characterized by the degeneration of dopamine neurons in the substantia nigra and …

Diagnostic utility of fluid biomarkers in multiple system atrophy: a systematic review and meta-analysis

S Cong, C Xiang, H Wang, S Cong - Journal of neurology, 2021 - Springer
Background Multiple system atrophy (MSA) is an adult onset, fatal neurodegenerative
disease. However, no reliable biomarker is currently available to guide clinical diagnosis …