Fever is a cardinal response to infection that has been conserved in warm-blooded and cold-
blooded vertebrates for more than 600 million years of evolution. The fever response is …

Schizophrenia is a serious mental illness with chronic symptoms and significant impairment
in psychosocial functioning. Although novel antipsychotics have been developed, the …

Cells in intestinal epithelia turn over rapidly due to damage from digestion and toxins
produced by the enteric microbiota. Gut homeostasis is maintained by intestinal stem cells …

Background Based on their capacity to suppress immune responses, multipotent
mesenchymal stromal cells (MSC) are intensively studied for various clinical applications …

The rapid spread of the SARS‐CoV‐2 pandemic poses particular challenges to the
management of persons with chronic disease. Reports of a possible neuroinvasiveness of …

Fever is a common symptom of infectious and inflammatory disease. It is well-established
that prostaglandin E2 is the final mediator of fever, which by binding to its EP3 receptor …

Global levels of obesity are reaching epidemic proportions, leading to a dramatic increase in
incidence of secondary diseases and the significant economic burden associated with their …

Glioblastoma multiforme (GBM) is a lethal cancer that responds poorly to radiotherapy and
chemotherapy. Glioma cancer-initiating cells have been shown to recapitulate the …

Fever is a cardinal symptom of infectious or inflammatory insults, but it can also arise from
noninfectious causes. The fever-inducing agent that has been used most frequently in …

Systemic inflammation-associated syndromes (eg, sepsis and septic shock) often have high
mortality and remain a challenge in emergency medicine. Systemic inflammation is usually …