• An overview of the current understanding of bleeding and thrombosis in cirrhosis.• An
evidence-based justification for bleeding risk assessment in patients with cirrhosis before …

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The prevention and management of bleeding and thrombosis in patients with cirrhosis
poses several difficult clinical questions. These Clinical Practice Guidelines have been …

This guidance provides a data-supported approach to risk stratification, diagnosis, and
management of patients with cirrhosis and portal hypertension (PH). A guidance document …

1 ESGE recommends that patients with compensated advanced chronic liver disease
(ACLD; due to viruses, alcohol, and/or nonobese [BMI< 30 kg/m 2] nonalcoholic …

Patients with cirrhosis frequently acquire complex changes in their haemostatic system
including a decreased platelet count and decreased levels of various haemostatic proteins …

The aims of severe perioperative bleeding management are three-fold. First, preoperative
identification by anamesis and laboratory testing of those patients for whom the …

Background & Aims Patients with cirrhosis with acute variceal bleeding (AVB) have high
mortality rates (15%–20%). Previously described models are seldom used to determine …

Gastroesophageal varices are present at diagnosis in almost half of patients with cirrhosis,
and variceal hemorrhage continues to be a lethal complication of cirrhosis. This review …

Background The use of recombinant activated factor VII (rFVIIa) on an off-label basis to treat
life-threatening bleeding has been associated with a perceived increased risk of …