High-density lipoprotein revisited: biological functions and clinical relevance
A von Eckardstein, BG Nordestgaard… - European heart …, 2023 - academic.oup.com
Previous interest in high-density lipoproteins (HDLs) focused on their possible protective
role in atherosclerotic cardiovascular disease (ASCVD). Evidence from genetic studies and …
role in atherosclerotic cardiovascular disease (ASCVD). Evidence from genetic studies and …
High density lipoproteins: metabolism, function, and therapeutic potential
High Density Lipoproteins (HDLs) have long been considered as “good cholesterol,”
beneficial to the whole body and, in particular, to cardio-vascular health. However, HDLs are …
beneficial to the whole body and, in particular, to cardio-vascular health. However, HDLs are …
Towards an SI-traceable reference measurement system for seven serum apolipoproteins using bottom-up quantitative proteomics: conceptual approach enabled by …
CM Cobbaert, H Althaus, I Begcevic Brkovic… - Clinical …, 2021 - academic.oup.com
Current dyslipidemia management in patients with atherosclerotic cardiovascular disease
(ASCVD) is based on traditional serum lipids. Yet, there is some indication from basic …
(ASCVD) is based on traditional serum lipids. Yet, there is some indication from basic …
[HTML][HTML] Non-alcoholic fatty liver disease is characterised by a reduced polyunsaturated fatty acid transport via free fatty acids and high-density lipoproteins (HDL)
G Mocciaro, M Allison, B Jenkins, V Azzu… - Molecular …, 2023 - Elsevier
Background and objectives Non-alcoholic fatty liver disease (NAFLD) develops due to
impaired hepatic lipid fluxes and is a risk factor for chronic liver disease and atherosclerosis …
impaired hepatic lipid fluxes and is a risk factor for chronic liver disease and atherosclerosis …
Solution structure of discoidal high-density lipoprotein particles with a shortened apolipoprotein AI
S Bibow, Y Polyhach, C Eichmann, CN Chi… - Nature structural & …, 2017 - nature.com
High-density lipoprotein (HDL) particles are cholesterol and lipid transport containers.
Mature HDL particles destined for the liver develop through the formation of intermediate …
Mature HDL particles destined for the liver develop through the formation of intermediate …
The role of cholesterol and mitochondrial bioenergetics in activation of the inflammasome in IBD
J Astorga, N Gasaly, K Dubois-Camacho… - Frontiers in …, 2022 - frontiersin.org
Inflammatory Bowel Disease (IBD) is characterized by a loss of intestinal barrier function
caused by an aberrant interaction between the immune response and the gut microbiota. In …
caused by an aberrant interaction between the immune response and the gut microbiota. In …
Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins
Triglyceride-rich lipoproteins (TRLs) are circulating reservoirs of fatty acids used as vital
energy sources for peripheral tissues. Lipoprotein lipase (LPL) is a predominant enzyme …
energy sources for peripheral tissues. Lipoprotein lipase (LPL) is a predominant enzyme …
Good cholesterol gone bad? HDL and COVID-19
GEG Kluck, JA Yoo, EH Sakarya, BL Trigatti - International journal of …, 2021 - mdpi.com
The transmissible respiratory disease COVID-19, caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has affected millions of people worldwide since its …
syndrome coronavirus 2 (SARS-CoV-2), has affected millions of people worldwide since its …
HDL functionality in reverse cholesterol transport—Challenges in translating data emerging from mouse models to human disease
M Lee-Rueckert, JC Escola-Gil, PT Kovanen - Biochimica et Biophysica …, 2016 - Elsevier
Whereas LDL-derived cholesterol accumulates in atherosclerotic lesions, HDL particles are
thought to facilitate removal of cholesterol from the lesions back to the liver thereby …
thought to facilitate removal of cholesterol from the lesions back to the liver thereby …
[HTML][HTML] ApoA1 and ApoA1-specific self-antibodies in cardiovascular disease
DA Chistiakov, AN Orekhov, YV Bobryshev - Laboratory Investigation, 2016 - Elsevier
Abstract Apolipoprotein A1 (ApoA1) is a main protein moiety in high-density lipoprotein
(HDL) particles. Generally, ApoA1 and HDL are considered as atheroprotective. In …
(HDL) particles. Generally, ApoA1 and HDL are considered as atheroprotective. In …