The mesolimbic dopamine system: the final common pathway for the reinforcing effect of drugs of abuse?
RC Pierce, V Kumaresan - Neuroscience & biobehavioral reviews, 2006 - Elsevier
In this review we will critically assess the hypothesis that the reinforcing effect of virtually all
drugs of abuse is primarily dependent on activation of the mesolimbic dopamine system …
drugs of abuse is primarily dependent on activation of the mesolimbic dopamine system …
Neuronal nicotinic receptors: from structure to pathology
C Gotti, F Clementi - Progress in neurobiology, 2004 - Elsevier
Neuronal nicotinic receptors (NAChRs) form a heterogeneous family of ion channels that are
differently expressed in many regions of the central nervous system (CNS) and peripheral …
differently expressed in many regions of the central nervous system (CNS) and peripheral …
Brain nicotinic acetylcholine receptors: native subtypes and their relevance
Neuronal nicotinic acetylcholine receptors comprise a heterogeneous class of cationic
channels that is present throughout the nervous system. These channels are involved both …
channels that is present throughout the nervous system. These channels are involved both …
Nicotine addiction and nicotinic receptors: lessons from genetically modified mice
JP Changeux - Nature Reviews Neuroscience, 2010 - nature.com
The past decades have seen a revolution in our understanding of brain diseases and in
particular of drug addiction. This has been largely due to the identification of …
particular of drug addiction. This has been largely due to the identification of …
Structural and functional diversity of native brain neuronal nicotinic receptors
C Gotti, F Clementi, A Fornari, A Gaimarri… - Biochemical …, 2009 - Elsevier
Neuronal nicotinic acetylcholine receptors (nAChRs) are a family of ligand-gated ion
channels present in the central and peripheral nervous systems, that are permeable to mono …
channels present in the central and peripheral nervous systems, that are permeable to mono …
Realistic expectations of prepulse inhibition in translational models for schizophrenia research
NR Swerdlow, M Weber, Y Qu, GA Light, DL Braff - Psychopharmacology, 2008 - Springer
Introduction Under specific conditions, a weak lead stimulus, or “prepulse”, can inhibit the
startling effects of a subsequent intense abrupt stimulus. This startle-inhibiting effect of the …
startling effects of a subsequent intense abrupt stimulus. This startle-inhibiting effect of the …
[HTML][HTML] Nicotine gateway effects on adolescent substance use
M Ren, S Lotfipour - Western Journal of Emergency Medicine, 2019 - ncbi.nlm.nih.gov
Given the rise in teenage use of electronic nicotine delivery systems (“vaping”) in
congruence with the increasing numbers of drug-related emergencies, it is critical to expand …
congruence with the increasing numbers of drug-related emergencies, it is critical to expand …
Diversity of vertebrate nicotinic acetylcholine receptors
Nicotinic acetylcholine receptors (nAChRs) are pentameric neurotransmitter receptors. They
are members of the Cys-loop family of ligand-gated ion channels which also include …
are members of the Cys-loop family of ligand-gated ion channels which also include …
Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations
AA Jensen, B Frølund, T Liljefors… - Journal of medicinal …, 2005 - ACS Publications
The neurotransmitter acetylcholine (ACh) exerts its effects on the central nervous system
(CNS) and peripheral nervous system (PNS) through two distinct types of receptors: the …
(CNS) and peripheral nervous system (PNS) through two distinct types of receptors: the …
Nicotine-induced upregulation of nicotinic receptors: underlying mechanisms and relevance to nicotine addiction
AP Govind, P Vezina, WN Green - Biochemical pharmacology, 2009 - Elsevier
A major hurdle in defining the molecular biology of nicotine addiction has been
characterizing the different nicotinic acetylcholine receptor (nAChR) subtypes in the brain …
characterizing the different nicotinic acetylcholine receptor (nAChR) subtypes in the brain …