Application of exosomes as liquid biopsy in clinical diagnosis
B Zhou, K Xu, X Zheng, T Chen, J Wang… - Signal transduction and …, 2020 - nature.com
Liquid biopsy refers to the sampling and molecular analysis of the biofluids of circulating
tumor cells, extracellular vesicles, nucleic acids, and so forth. Exosomes are small …
tumor cells, extracellular vesicles, nucleic acids, and so forth. Exosomes are small …
Role of exosomes in the pathogenesis, diagnosis, and treatment of central nervous system diseases
Y Fan, Z Chen, M Zhang - Journal of Translational Medicine, 2022 - Springer
Central nervous system (CNS) diseases, such as multiple sclerosis, Alzheimer's disease
(AD), and Parkinson's disease (PD), affect millions of people around the world. Great efforts …
(AD), and Parkinson's disease (PD), affect millions of people around the world. Great efforts …
[HTML][HTML] Exosomal miRNAs in central nervous system diseases: biomarkers, pathological mediators, protective factors and therapeutic agents
Exosomes are small bilipid layer-enclosed extracellular vesicles that can be found in tissues
and biological fluids. As a key cell-to-cell and distant communication mediator, exosomes …
and biological fluids. As a key cell-to-cell and distant communication mediator, exosomes …
MicroRNAs: roles in regulating neuroinflammation
MicroRNAs (miRNAs) are small noncoding RNAs that broadly affect cellular and
physiological function in all multicellular organisms. Here, the role of miRNAs in …
physiological function in all multicellular organisms. Here, the role of miRNAs in …
Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions
Brain injury induces a peripheral acute cytokine response that directs the transmigration of
leukocytes into the brain. Because this brain-to-peripheral immune communication affects …
leukocytes into the brain. Because this brain-to-peripheral immune communication affects …
Glioma-derived miRNA-containing extracellular vesicles induce angiogenesis by reprogramming brain endothelial cells
R Lucero, V Zappulli, A Sammarco, OD Murillo… - Cell reports, 2020 - cell.com
Glioblastoma (GBM) is characterized by aberrant vascularization and a complex tumor
microenvironment. The failure of anti-angiogenic therapies suggests pathways of GBM …
microenvironment. The failure of anti-angiogenic therapies suggests pathways of GBM …
A critical systematic review of extracellular vesicle clinical trials
RR Mizenko, M Feaver, BT Bozkurt… - Journal of …, 2024 - Wiley Online Library
This systematic review examines the landscape of extracellular vesicle (EV)‐related clinical
trials to elucidate the field's trends in clinical applications and EV‐related methodologies …
trials to elucidate the field's trends in clinical applications and EV‐related methodologies …
MicroRNAs as diagnostic and prognostic biomarkers in ischemic stroke—a comprehensive review and bioinformatic analysis
Stroke is the second-most common cause of death worldwide. The pathophysiology of
ischemic stroke (IS) is related to inflammation, atherosclerosis, blood coagulation, and …
ischemic stroke (IS) is related to inflammation, atherosclerosis, blood coagulation, and …
Advanced nanotechnologies for extracellular vesicle‐based liquid biopsy
Extracellular vesicles (EVs) are emerging as a new source of biomarkers in liquid biopsy
because of their wide presence in most body fluids and their ability to load cargoes from …
because of their wide presence in most body fluids and their ability to load cargoes from …
A systematic review of the research progress of non-coding RNA in neuroinflammation and immune regulation in cerebral infarction/ischemia-reperfusion injury
K Yang, L Zeng, A Ge, S Wang, J Zeng, X Yuan… - Frontiers in …, 2022 - frontiersin.org
Cerebral infarction/ischemia-reperfusion injury is currently the disease with the highest
mortality and disability rate of cardiovascular disease. Current studies have shown that …
mortality and disability rate of cardiovascular disease. Current studies have shown that …