Toll-like receptor pathways in autoimmune diseases

JQ Chen, P Szodoray, M Zeher - Clinical reviews in allergy & immunology, 2016 - Springer
Autoimmune diseases are a family of chronic systemic inflammatory disorders, characterized
by the dysregulation of the immune system which finally results in the break of tolerance to …

[HTML][HTML] Nutrition interventions in rheumatoid arthritis: the potential use of plant-based diets. A review

J Alwarith, H Kahleova, E Rembert, W Yonas… - Frontiers in …, 2019 - frontiersin.org
Rheumatoid arthritis (RA), a chronic inflammatory autoimmune disease, affects roughly 1%
of the world's population. RA pathogenesis remains unclear, but genetic factors account for …

[HTML][HTML] Managing rheumatoid arthritis with dietary interventions

S Khanna, KS Jaiswal, B Gupta - Frontiers in nutrition, 2017 - frontiersin.org
Self-help by means of dietary interventions can help in management of various disorders
including rheumatoid arthritis (RA), a debilitating autoimmune disease. Dietary interventions …

A randomized, placebo-controlled experimental medicine study of RIPK1 inhibitor GSK2982772 in patients with moderate to severe rheumatoid arthritis

K Weisel, S Berger, K Thorn, PC Taylor… - Arthritis research & …, 2021 - Springer
Background Receptor-interacting protein kinase 1 (RIPK1) is a key mediator of inflammation
through cell death and proinflammatory cytokine production. This multicenter, randomized …

Phytochemicals against TNFα-Mediated Neuroinflammatory Diseases

L Subedi, SE Lee, S Madiha, BP Gaire, M Jin… - International journal of …, 2020 - mdpi.com
Tumor necrosis factor-alpha (TNF-α) is a well-known pro-inflammatory cytokine responsible
for the modulation of the immune system. TNF-α plays a critical role in almost every type of …

TRAF molecules in inflammation and inflammatory diseases

AI Lalani, S Zhu, S Gokhale, J Jin, P Xie - Current Pharmacology Reports, 2018 - Springer
Abstract Purpose of Review This review presents an overview of the current knowledge of
tumor necrosis factor receptor (TNF-R)-associated factor (TRAF) molecules in inflammation …

Role of natural products in alleviation of rheumatoid arthritis—A review

D Sharma, P Chaubey… - Journal of food …, 2021 - Wiley Online Library
Rheumatoid arthritis (RHA) is one of the most prevalent complex, chronic, inflammatory
diseases, manifested by elevated oxidative stress and inflammatory biomarkers. Prolonged …

Tumor necrosis factor–α is a common genetic risk factor for asthma, juvenile rheumatoid arthritis, and systemic lupus erythematosus in a Mexican pediatric population

S JimÊnez-Morales, R VelÂzquez-Cruz… - Human immunology, 2009 - Elsevier
There is a great deal of evidence that points to the association of the tumor necrosis factor-
alpha (TNF-α) gene as a common genetic factor in the pathogenesis of diseases that are …

TNF-α affects signature cytokines of Th1 and Th17 T cell subsets through differential actions on TNFR1 and TNFR2

B Pesce, CH Ribeiro, M Larrondo, V Ramos… - International Journal of …, 2022 - mdpi.com
Tumor necrosis factor (TNF)-α is a pleiotropic cytokine implicated in the etiology of several
autoimmune diseases, including rheumatoid arthritis (RA). TNF-α regulates diverse effector …

[HTML][HTML] Diet and lifestyle impact on rheumatoid arthritis: a comprehensive review

KV Shekhar, MM Pathak, G Pisulkar - Cureus, 2023 - ncbi.nlm.nih.gov
A systemic, inflammatory illness such as rheumatoid arthritis (RA) causes progressive
cartilage and bone degradation in addition to joint involvement. Factors related to genetics …