Hippuric acid (HA) is a metabolite resulting from the hepatic glycine conjugation of benzoic
acid (BA) or from the gut bacterial metabolism of phenylalanine. BA is generally produced by …

Background Oncogenic transformation alters intracellular metabolism and contributes to the
growth of malignant cells. Metabolomics, or the study of small molecules, can reveal insight …

The direct and unambiguous detection and identification of individual metabolite molecules
present in complex biological mixtures constitute a major challenge in (bio) analytical …

Colorectal cancer (CRC) is a common malignant tumor in the gastrointestinal tract. Changes
in amino acid metabolites have been implicated in tumorigenesis and disease progression …

Nuclear magnetic resonance (NMR)-based metabolomics is a valuable tool for identifying
biomarkers and understanding the underlying metabolic changes associated with various …

Objective: The purpose of this study was to employ metabolomics for the analysis of urine
metabolites in swimmers, with the aim of establishing models for assessing their athletic …

Background Understanding the metabolic changes in colorectal cancer (CRC) and
exploring potential diagnostic biomarkers is crucial for elucidating its pathogenesis and …

The technological advances of recent years have significantly enhanced medical
discoveries. In particular, biomedical research has been largely supported by the omics …

Abstract Treatment response assessment of rectal cancer patients is a critical component of
personalized cancer care and it allows to identify suitable candidates for organ-preserving …

Abstract Urinary N 1, N 12-diacetylspermine (DAS) is a known biomarker for colorectal
cancer (CRC). However, DAS levels in both healthy and CRC patients' urine samples are …