The development of immune-checkpoint inhibitors (ICIs) has heralded a new era in cancer
treatment, enabling the possibility of long-term survival in patients with metastatic disease …

With immune checkpoint inhibitors (ICIs) becoming the mainstay of treatment for many
cancers, managing their immune-related adverse events (irAEs) has become an important …

Highlights•This review collected the available evidence on the role of immunotherapy on
fertility, hypogonadism, and sexuality.•Immune checkpoint inhibitors could impair fertility.• …

The addition of immune checkpoint inhibitors (ICIs) to the therapeutic armamentarium for
solid malignancies has resulted in unprecedented improvements in patient outcomes in …

The human conceptus is a semi-allograft, which is antigenically foreign to the mother.
Hence, the implantation process needs mechanisms to prevent allograft rejection during …

Objective The aim of this case-based clinical review was to provide a practical approach for
clinicians regarding the management of patients with immune checkpoint inhibitor (ICI) …

Background: Over the past decades, advancements in oncological treatments have led to
major improvements in survival. Particularly for adolescents and young adults (AYAs) …

Cancer and oncologic therapies can have significant adverse effects on male reproductive
potential, leaving many men permanently infertile. Fertility preservation has emerged as a …

Cutaneous melanoma, the most aggressive type of skin cancer, remains one the most
represented forms of cancer in the United States and European countries, representing, in …

Despite a significant amount of data on incidence and therapy of immune-related adverse
events affecting virtually all organ systems, the potential impact of immune checkpoint …