The transmissible spongiform encephalopathies of livestock

JJ Greenlee, MHW Greenlee - ILAR journal, 2015 - academic.oup.com
Prion diseases or transmissible spongiform encephalopathies (TSEs) are fatal protein-
misfolding neurodegenerative diseases. TSEs have been described in several species …

A review of selected genes with known effects on performance and health of cattle

E Casas, ME Kehrli Jr - Frontiers in veterinary science, 2016 - frontiersin.org
There are genetic conditions that influence production in dairy and beef cattle. The objective
of this review was to describe relevant genetic conditions that have been associated with …

Experimental transmission of the chronic wasting disease agent to swine after oral or intracranial inoculation

SJ Moore, MH West Greenlee, N Kondru… - Journal of …, 2017 - Am Soc Microbiol
Chronic wasting disease (CWD) is a naturally occurring, fatal neurodegenerative disease of
cervids. The potential for swine to serve as hosts for the agent of CWD is unknown. The …

Pathologic and biochemical characterization of PrPSc from elk with PRNP polymorphisms at codon 132 after experimental infection with the chronic wasting disease …

SJ Moore, CE Vrentas, S Hwang… - BMC veterinary …, 2018 - Springer
Abstract Background The Rocky Mountain elk (Cervus elaphus nelsoni) prion protein gene
(PRNP) is polymorphic at codon 132, with leucine (L132) and methionine (M132) allelic …

Sporadic cases of chronic wasting disease in old moose–an epidemiological study

P Hopp, CM Rolandsen… - Journal of General …, 2024 - microbiologyresearch.org
Transmissible spongiform encephalopathies or prion diseases comprise diseases with
different levels of contagiousness under natural conditions. The hypothesis has been raised …

First Report of the Potential Bovine Spongiform Encephalopathy (BSE)-Related Somatic Mutation E211K of the Prion Protein Gene (PRNP) in Cattle

SY Won, YC Kim, BH Jeong - International journal of molecular sciences, 2020 - mdpi.com
Bovine spongiform encephalopathy (BSE) is a prion disease characterized by spongiform
degeneration and astrocytosis in the brain. Unlike classical BSE, which is caused by prion …

Temporal resolution of misfolded prion protein transport, accumulation, glial activation, and neuronal death in the retinas of mice inoculated with scrapie

MHW Greenlee, M Lind, R Kokemuller… - The American journal of …, 2016 - Elsevier
Currently, there is a lack of pathological landmarks to describe the progression of prion
disease in vivo. Our goal was to use an experimental model to determine the temporal …

Raccoons accumulate PrPSc after intracranial inoculation of the agents of chronic wasting disease or transmissible mink encephalopathy but not atypical scrapie

SJ Moore, JD Smith, JA Richt… - Journal of Veterinary …, 2019 - journals.sagepub.com
Prion diseases are neurodegenerative diseases characterized by the accumulation of
misfolded prion protein (PrPSc) in the brain and other tissues. Animal prion diseases include …

Differential accumulation of misfolded prion strains in natural hosts of prion diseases

ZJ Lambert, JJ Greenlee, ED Cassmann… - Viruses, 2021 - mdpi.com
Prion diseases, also known as transmissible spongiform encephalopathies (TSEs), are a
group of neurodegenerative protein misfolding diseases that invariably cause death. TSEs …

[HTML][HTML] Increased attack rates and decreased incubation periods in raccoons with chronic wasting disease passaged through meadow voles

SJ Moore, CM Carlson, JR Schneider… - Emerging Infectious …, 2022 - ncbi.nlm.nih.gov
Chronic wasting disease (CWD) is a naturally-occurring neurodegenerative disease of
cervids. Raccoons (Procyon lotor) and meadow voles (Microtus pennsylvanicus) have …