Genomics of cardiovascular disease
CJ O'Donnell, EG Nabel - New England journal of medicine, 2011 - Mass Medical Soc
Genomics of Cardiovascular Disease | New England Journal of Medicine Skip to main content
The New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …
The New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …
Abdominal aortic aneurysm: novel mechanisms and therapies
FM Davis, DL Rateri, A Daugherty - Current opinion in cardiology, 2015 - journals.lww.com
Abdominal aortic aneurysm: novel mechanisms and therapies : Current Opinion in
Cardiology Abdominal aortic aneurysm: novel mechanisms and therapies : Current Opinion …
Cardiology Abdominal aortic aneurysm: novel mechanisms and therapies : Current Opinion …
Association between telomere length and risk of cancer and non-neoplastic diseases: a Mendelian randomization study
Importance The causal direction and magnitude of the association between telomere length
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …
Meta-analysis of genome-wide association studies for abdominal aortic aneurysm identifies four new disease-specific risk loci
Rationale: Abdominal aortic aneurysm (AAA) is a complex disease with both genetic and
environmental risk factors. Together, 6 previously identified risk loci only explain a small …
environmental risk factors. Together, 6 previously identified risk loci only explain a small …
Genetics of thoracic aortic aneurysm: at the crossroad of transforming growth factor-β signaling and vascular smooth muscle cell contractility
E Gillis, L Van Laer, BL Loeys - Circulation research, 2013 - Am Heart Assoc
Aortic aneurysm, including both abdominal aortic aneurysm and thoracic aortic aneurysm, is
the cause of death of 1% to 2% of the Western population. This review focuses only on …
the cause of death of 1% to 2% of the Western population. This review focuses only on …
Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm
S Gretarsdottir, AF Baas, G Thorleifsson, H Holm… - Nature …, 2010 - nature.com
We performed a genome-wide association study on 1,292 individuals with abdominal aortic
aneurysms (AAAs) and 30,503 controls from Iceland and The Netherlands, with a follow-up …
aneurysms (AAAs) and 30,503 controls from Iceland and The Netherlands, with a follow-up …
Understanding the effects of tobacco smoke on the pathogenesis of aortic aneurysm
Aneurysmal arterial disease is a vascular degenerative condition that is distinct from
atherosclerotic and other occlusive arterial diseases. There is regionalization of the …
atherosclerotic and other occlusive arterial diseases. There is regionalization of the …
Genetic and epigenetic regulation of aortic aneurysms
HW Kim, BK Stansfield - BioMed Research International, 2017 - Wiley Online Library
Aneurysms are characterized by structural deterioration of the vascular wall leading to
progressive dilatation and, potentially, rupture of the aorta. While aortic aneurysms often …
progressive dilatation and, potentially, rupture of the aorta. While aortic aneurysms often …
A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm
Abdominal aortic aneurysm (AAA) is a common human disease with a high estimated
heritability (0.7); however, only a small number of associated genetic loci have been …
heritability (0.7); however, only a small number of associated genetic loci have been …
The genetic basis for aortic aneurysmal disease
A Saratzis, MJ Bown - Heart, 2014 - heart.bmj.com
Aortic aneurysms are an important cause of cardiovascular death in elderly patients. At
present, little is known of the pathobiology of aneurysmal disease and this limits the ability to …
present, little is known of the pathobiology of aneurysmal disease and this limits the ability to …