The autonomic nervous system plays an important role in the modulation of cardiac
electrophysiology and arrhythmogenesis. Decades of research has contributed to a better …

Autonomic nervous system activation can induce significant and heterogeneous changes of
atrial electrophysiology and induce atrial tachyarrhythmias, including atrial tachycardia and …

Dysfunction of the autonomic nervous system has been implicated in the pathogenesis of
cardiovascular disease, including congestive heart failure and cardiac arrhythmias. Despite …

The autonomic nervous system regulates all aspects of normal cardiac function, and is
recognized to play a critical role in the pathophysiology of many cardiovascular diseases. As …

Background Left and bilateral cardiac sympathetic denervation (CSD) have been shown to
reduce burden of ventricular arrhythmias acutely in a small number of patients with …

The vagus nerve plays an important role in maintaining physiological homeostasis, which
includes reflex pathways that regulate cardiac function. The link between vagus nerve …

Neuronal elements distributed throughout the cardiac nervous system, from the level of the
insular cortex to the intrinsic cardiac nervous system, are in constant communication with …

Key points Intrinsic cardiac (IC) neurons undergo differential morphological and phenotypic
remodelling that reflects the site of myocardial infarction (MI). Afferent neural signals from the …

AF is a heterogeneous rhythm disorder that is related to a wide spectrum of etiologies and
has broad clinical presentations. Mechanisms underlying AF are complex and remain …

Ischemic heart disease is the most common cause of lethal ventricular arrhythmias and
sudden cardiac death (SCD). In patients who are at high risk after myocardial infarction …