Phosphoinositides are lipids involved in the vesicular transport of proteins and lipids
between the different compartments of eukaryotic cells. They act by recruiting and/or …

Phosphoinositides are a collection of lipid messengers that regulate most subcellular
processes. Amongst the seven phosphoinositide species, the roles for phosphatidylinositol …

Nuclear speckles are small, membrane-less organelles that reside within the nucleus.
Nuclear speckles serve as a regulatory hub coordinating complex RNA metabolism steps …

In eukaryotes, almost all RNA species are processed at their 3′ ends and most mRNAs are
polyadenylated in the nucleus by canonical poly (A) polymerases. In recent years, several …

Termini often determine the fate of RNA molecules. In recent years, 3′ ends of almost all
classes of RNA species have been shown to acquire nontemplated nucleotides that are …

Polyphosphoinositides (PPIns) are a family of seven lipid messengers that regulate a vast
array of signalling pathways to control cell proliferation, migration, survival and …

Abstract Phosphatidylinositol 4, 5-bisphosphate (PI4, 5P 2) is an essential lipid messenger
with roles in all eukaryotes and most aspects of human physiology. By controlling the …

Phosphatidylinositol (PtdIns) metabolism is indispensable in eukaryotes. Phosphoinositides
(PIs) are phosphorylated derivatives of PtdIns and consist of seven species generated by …

Phosphatidylinositol 4, 5-bisphosphate [PI (4, 5) P 2] is a multi-functional lipid that regulates
several essential subcellular processes in eukaryotic cells. In addition to its well-established …

Recent advances reveal mRNA 3′ end processing as a highly regulated process that fine‐
tunes posttranscriptional gene expression. This process can affect the site and/or the …